Detection of Vocal Fold Motion Impairment on Noninvasive Positive Pressure

Conditions

• Recurrent Laryngeal Nerve Injuries
• Recurrent Laryngeal Nerve Palsy
• Vocal Cord Dysfunction
• Vocal Cord Paralysis
• Vocal Cord Paresis

Eligibility Criteria

Sex

ALL

Age

1 Day - 18 Years

Healthy Volunteers

Accepted

Interventions

• Point-of-Care Ultrasound of the Airway — DIAGNOSTIC_TEST
  Patients who are recruited will have an ultrasound performed of their larynx while they are on noninvasive positive pressure ventilation and then a second ultrasound when they are removed from noninvasive positive pressure ventilation. Between the two ultrasounds, the otolaryngology team will perform their fiberoptic nasolaryngoscopy, as per standard unit protocol and patient care.

Study Details

The goal of this prospective, observational study is to evaluate for the presence of vocal fold motion impairment (VFMI) in the children admitted to the pediatric intensive care unit on noninvasive positive pressure ventilation (NIV PPV). Participants will have two ultrasounds of their vocal folds performed, once while on NIV PPV and once after weaned off of the NIV PPV. This results of these scans will be reviewed against one another and against the gold standard, fiberoptic nasolaryngoscopy (FNL). The main question this study aims to answer is: Can POCUS be used to reliably detect VFMI while pediatric patients on supported with NIV PPV?

Key Dates

Start date

Mar 30, 2024

Status verified

Apr 2026

Primary completion

Mar 30, 2028

Completion

May 30, 2028

Study Design

Enrollment

50 participants (estimated)

Arms

• Arm: NIV PPV
  We will recruit patients who are currently on noninvasive positive pressure ventilation (NIV PPV) who are scheduled for fiberoptic nasolaryngoscopy (FNL) with the otolaryngology team for evaluation of vocal fold motion impairment (VFMI).

Primary Outcome Measure

VFMI [ Time Frame: 2 years ]

Central Contacts

• April Slamowitz, MD
  718-470-3000
  [email protected]
• Catherine Geller, MD
  718-470-3000
  [email protected]

Locations (1)

Find similar trials in Queens, NY

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