Regional Lipolysis Insulin Regulation

Part of paid clinical trials in Rochester, Minnesota.

Sponsor
Mayo Clinic
Study ID
NCT06392854
Phase
EARLY_PHASE1
Status
Recruiting

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 65 Years
Healthy Volunteers
Accepted

Interventions

  • Insulin — DRUG
    2 dose insulin infusion 4 hours

Study Details

Adults who gain most of their excess weight in the abdominal area typically do not respond to insulin in the same way as lean adults. Researchers are trying to understand why fat tissue responds differently in people with different body types.

Key Dates

Start date
May 1, 2024
Status verified
Apr 2026
Primary completion
Jun 30, 2028
Completion
Jun 30, 2028

Study Design

Enrollment
48 participants (estimated)
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE

Arms

  • Other: obesity status
    obesity
  • Other: lean
    non-obese

Primary Outcome Measure

palmitate release [ Time Frame: The study will be conducted in a single day and will last approximately 6 hours ]

Locations (1)

FacilityCityStateZIPSite coordinators
Mayo Clinic in RochesterRochesterMinnesota55905
Madeline S Reid
507-255-0007
Michael D Jensen, MD (PRINCIPAL_INVESTIGATOR)

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