COmparison of Clarus and Optos Ultrawide Field Imaging Systems for Inherited Retinal Disease

Part of paid clinical trials in Madison, Wisconsin.

Sponsor
University of Wisconsin, Madison
Study ID
NCT06380075
Status
Recruiting
Apply to this trial

Conditions

  • Retinal Disease

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Spectralis FAF imaging — DEVICE
    Spectralis is a scanning laser ophthalmoscope which uses a blue light excitation wavelength of 488nm and a 500nm barrier filter to produce FAF images. Spectralis images 20-55 degrees of the retina.
  • Optos imaging — DEVICE
    Optos is an ultrawide field imaging platform which images up to 200 degrees of the retina. It uses both a green-light excitation wavelength of 532nm and a red-light excitation wavelength of 633nm with an emission filter of greater than 540nm to produce FAF images.
  • Clarus imaging — DEVICE
    Clarus 700 is an ultrawide field imaging system with similar retinal coverage to that of Optos. It uses Broad Line Fundus Imaging to produce blue FAF images at excitation wavelengths of 435-500nm and green FAF images at wavelengths of 500-585nm

Study Details

The goal of this research study is to compare two ultrawide field cameras to the gold standard imaging system to evaluate the back of the eye. The main question it aims to answer is the same results and information can be acquired from all of the cameras for evaluating and monitoring inherited retinal diseases (IRDs). Participants will: * undergo pupillary dilation * have photographs taken of the inside of the eyes using three different cameras

Key Dates

Start date
Aug 29, 2024
Status verified
Apr 2026
Primary completion
Dec 31, 2026
Completion
Dec 31, 2026

Study Design

Enrollment
50 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER

Arms

  • Experimental: Fundus autofluorescence (FAF) imaging

Primary Outcome Measure

Compare FAF retinal patterns by Clarus and standard Spectralis FAF imaging [ Time Frame: Up to 2 hours ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Department of Ophthalmology and Visual SciencesMadisonWisconsin53705
Amy Remm
[email protected]
608-262-3377
Kimberly Stepien, MD (PRINCIPAL_INVESTIGATOR)

Find similar trials in Madison, WI

By research site
Department of Ophthalmology and Visual Sciences· Madison, WI

Related Studies