The Effects of Healthy Diets With Plant Oils on Heart and Metabolic Health

Part of paid clinical trials in University Park, Pennsylvania.

Sponsor
Penn State University
Study ID
NCT06216678
Status
Recruiting
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Conditions

  • Cardiovascular Diseases

Eligibility Criteria

Sex
ALL
Age
25 Years - 60 Years
Healthy Volunteers
Accepted

Interventions

  • Healthy Dietary Pattern with Cottonseed Oil — OTHER
    Cottonseed Oil
  • Healthy Dietary Pattern with Fatty Acid-Matched Plant Oils — OTHER
    Plant oil blend fatty acid matched
  • Healthy Dietary Pattern with PUFA:SFA Ratio-Matched Plant Oil — OTHER
    Plant oil with matched PUFA to SFA ratio

Study Details

This study will examine the effect of a healthy diet containing cottonseed oil compared to healthy diets containing other commonly consumed plant oils on biomarkers of heart and metabolic health after 4 weeks.

Key Dates

Start date
Sep 9, 2024
Status verified
Jan 2026
Primary completion
Dec 31, 2027
Completion
Dec 31, 2027

Study Design

Enrollment
52 participants (estimated)
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION

Arms

  • Experimental: Healthy Diet + Cottonseed Oil (CSOD)
    Healthy dietary pattern containing 40g/day/2000 kcal of cottonseed oil (CSO)
  • Active Comparator: Healthy Diet + Fatty Acid-Matched Plant Oils (FAMD)
    Healthy dietary pattern containing 40g/day/2000 kcal of a blend of plant oils comprising a fatty acid profile that matches the CSOD but devoid of CSO
  • Active Comparator: Healthy Diet + PUFA:SFA Ratio-Matched Plant Oil (P:S-MD)
    Healthy dietary pattern containing 40g/day/2000 kcal of plant oil that is lower in polyunsaturated fatty acids (PUFA) and saturated fatty acids (SFA) than the CSOD, but with a matched PUFA:SFA ratio and devoid of CSO.

Primary Outcome Measure

LDL-cholesterol concentration [ Time Frame: 4 weeks ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
The Pennylvania State UniversityUniversity ParkPennsylvania16802
[email protected]
1-866-778-3438

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By research site
The Pennylvania State University· University Park, PA

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