Brain Connections for Arm Movement After Stroke

Part of paid clinical trials in Pittsburgh, Pennsylvania.

Sponsor
VA Office of Research and Development
Study ID
NCT04286516
Status
Recruiting

Conditions

  • Brain Disease
  • Cardiovascular Diseases
  • Central Nervous System Diseases
  • Nervous System Diseases
  • Stroke

Eligibility Criteria

Sex
ALL
Age
45 Years - 90 Years
Healthy Volunteers
Accepted

Interventions

  • Transcranial Magnetic Stimulation — DEVICE
    Paired pulse transcranial magnetic stimulation

Study Details

The purpose of this study is to use Transcranial Magnetic Stimulation (TMS) while subjects are making reaching movements in a robotic arm device in order to discover how different brain areas control movement before and after stroke and when these brain areas are most sensitive to TMS.

Key Dates

Start date
Jan 10, 2020
Status verified
May 2026
Primary completion
Sep 1, 2026
Completion
Jun 1, 2027

Study Design

Enrollment
76 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Reaching with TMS
    All participants enrolled in this group will receive TMS while performing reaching movements in a robotic system.

Primary Outcome Measure

Path length [ Time Frame: Immediate (within 2 s after stimulation) ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PAPittsburghPennsylvania15240
George F Wittenberg, MD PhD
(412) 360-6185
Amy Boos
(412) 648-4179
George F. Wittenberg, MD PhD (PRINCIPAL_INVESTIGATOR)

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