Human Laboratory Study of the Effects of Nicotine Product Claims on Appeal, Perceptions, and Use Behavior

Conditions

• Behavior, Risk

Eligibility Criteria

Sex

ALL

Age

18 Years - 65 Years

Healthy Volunteers

Accepted

Interventions

• 3x3 between-subjects experimental exposure — BEHAVIORAL
  Participants will be randomly assigned to conditions in a 3 (Nicotine Concentration: None on label, Low, High) x 3 (Nicotine Source Claim: None, "Tobacco Free," "Synthetic Nicotine") between-subjects design. We will stratify randomization by young adult susceptible non-users and adult tobacco users for balance across the conditions. Participants will view 16 oral nicotine pouch pack images in random order that correspond to the nicotine concentration and source claim condition they are randomized to. Within each condition, pack images will vary by 4 brands and 4 flavors per brand. While viewing the images, we will collect psychophysiological data including heart rate, galvanic skin response, and eye tracking.

Study Details

This study evaluates knowledge, feelings and thoughts regarding nicotine products among young adults who are susceptible to but do not use tobacco/nicotine and adults who use tobacco/nicotine.

Key Dates

Start date

Mar 1, 2024

Status verified

Feb 2026

Primary completion

Sep 14, 2028

Completion

Sep 14, 2028

Study Design

Enrollment

450 participants (estimated)

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Arms

• Experimental: Nicotine Concentration: None Displayed; Nicotine Source Claim 1
  Participants view randomized images of nicotine-containing product packaging and complete a lapse task test on study. Participants also complete questionnaires on study.
• Experimental: Nicotine Concentration: None Displayed; Nicotine Source Claim 2
  Participants view randomized images of nicotine-containing product packaging and complete a lapse task test on study. Participants also complete questionnaires on study.
• Experimental: Nicotine Concentration: None Displayed; Nicotine Source Claim 3
  Participants view randomized images of nicotine-containing product packaging and complete a lapse task test on study. Participants also complete questionnaires on study.
• Experimental: Nicotine Concentration: Low; Nicotine Source Claim 1
  Participants view randomized images of nicotine-containing product packaging and complete a lapse task test on study. Participants also complete questionnaires on study.
• Experimental: Nicotine Concentration: Low; Nicotine Source Claim 2
  Participants view randomized images of nicotine-containing product packaging and complete a lapse task test on study. Participants also complete questionnaires on study.
• Experimental: Nicotine Concentration: Low; Nicotine Source Claim 3
  Participants view randomized images of nicotine-containing product packaging and complete a lapse task test on study. Participants also complete questionnaires on study.
• Experimental: Nicotine Concentration: High; Nicotine Source Claim 1
  Participants view randomized images of nicotine-containing product packaging and complete a lapse task test on study. Participants also complete questionnaires on study.
• Experimental: Nicotine Concentration: High; Nicotine Source Claim 2
  Participants view randomized images of nicotine-containing product packaging and complete a lapse task test on study. Participants also complete questionnaires on study.
• Experimental: Nicotine Concentration: High; Nicotine Source Claim 3
  Participants view randomized images of nicotine-containing product packaging and complete a lapse task test on study. Participants also complete questionnaires on study.

Primary Outcome Measure

Visual Attention - Dwell Time [ Time Frame: 1 day (Single Time Point: During Exposure) ]

Central Contacts

• The Ohio State University Comprehensive Cancer Center
  800-293-5066
  [email protected]

Locations (1)

Find similar trials in Columbus, OH

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