Teen Brain Training (TBT)

Part of paid clinical trials in Minneapolis, Minnesota.

Sponsor
University of Minnesota
Study ID
NCT06183580
Phase
PHASE1
Status
Completed

Conditions

Eligibility Criteria

Sex
ALL
Age
11 Years - 18 Years
Healthy Volunteers
Accepted

Interventions

  • neurofeedback training involving dACC — OTHER
    Participants are pseudorandomized to the dACC group to undergo neurofeedback (NF). NF training consists of four \~7.33 min NF training runs preceded by a 5 min baseline (no NF) and followed by a 5 min transfer run (no NF). Training entails NF blocks paired to a self-happy face along a bar that indicates changing levels of the dACC. During the control condition, participants will count backward (CB) from 100 cued by an unfamiliar happy face with no NF. During rest conditions, participants see the cue "Rest" and are asked to relax with their eyes open. During NF, participants will try to increase dACC neural activity by recalling happy memories. The colored bar indicating the neural activity will shift up or down depending on values provided by Turbo-BrainVoyager software. Green = Activity \> baseline and red = Activity \< baseline. Before and after NF training, suicide ideation severity, depression severity, and performance on self-processing behavioral tasks will be assessed.
  • neurofeedback training involving amygdala — OTHER
    Participants are pseudorandomized to the rAMY group to undergo neurofeedback (NF). NF training consists of four \~7.33 min NF training runs preceded by a 5 min baseline (no NF) and followed by a 5 min transfer run (no NF). Training entails NF blocks paired to a self-happy face along a bar that indicates changing levels of the rAMY. During the control condition, participants will count backward (CB) from 100 cued by an unfamiliar happy face with no NF. During rest conditions, participants see the cue "Rest" and are asked to relax with their eyes open. During NF, participants will try to increase rAMY neural activity by recalling happy memories. The colored bar indicating the neural activity will shift up or down depending on values provided by Turbo-BrainVoyager software. Green = Activity \> baseline and red = Activity \< baseline. Before and after NF training, suicide ideation severity, depression severity, and performance on self-processing behavioral tasks will be assessed.

Study Details

A non invasive treatment study including participants at risk for suicide attempts and undergoing neurofeedback training. Neurofeedback is controlling your brain activity in real time inside the scanner.

Key Dates

Start date
May 28, 2022
Status verified
Mar 2026
Primary completion
Feb 18, 2024
Completion
Feb 18, 2024

Study Design

Enrollment
157 participants (actual)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: dACC Arm
    Participants assigned to the Neurofeedback from the dorsal anterior cingulate cortex
  • Experimental: rAMY Arm
    Participants assigned to the Neurofeedback from the amygdala

Primary Outcome Measure

Columbia Suicide Severity Rating Scale (CSSRS) - Visit 1 [ Time Frame: Day 0 ]

Locations (1)

FacilityCityStateZIPSite coordinators
University of MinnesotaMinneapolisMinnesota55414-

Find similar trials in Minneapolis, MN

By condition
Depression
By specialty
PsychiatryMental healthBehavioral health
By research site
University of Minnesota· Minneapolis, MN

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