Transdiagnostic Cognitive Biomarkers
Part of paid clinical trials in Minneapolis, Minnesota.
- Sponsor
- University of Minnesota
- Study ID
- NCT04864080
- Status
- Recruiting
Conditions
- Depression
- Pain
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - N/A
- Healthy Volunteers
- Accepted
Interventions
- Computer game/task — BEHAVIORALN-back, COGED, PacMan game, Bandit task, Websurf task.
- Health surveys online — BEHAVIORALHealth surveys to study themes like pain, sleep, depression and anxiety, and PTSD.
Study Details
The overall objective of this study is to determine the feasibility of identifying transdiagnostic biomarkers of cognitive function mediated by neuromodulation of the dorsolateral prefrontal cortex that are translatable across disease groups in order to more accurately phenotype clusters of cognitive dysfunction. Completing behavioral paradigms with electrophysiology and TMS is a challenging frontier. This study focuses on the feasibility of such an endeavor for those with chronic pain or depression as well as healthy controls.
Key Dates
- Start date
- Apr 11, 2022
- Status verified
- Mar 2026
- Primary completion
- Mar 1, 2027
- Completion
- Mar 1, 2027
Study Design
- Enrollment
- 45 participants (estimated)
- Allocation
- NON_RANDOMIZED
- Intervention model
- SINGLE_GROUP
- Primary purpose
- DIAGNOSTIC
Arms
- Active Comparator: Healthy Comparison GroupBehavioral tasks and surveys online.
- Experimental: Pain/Depression patients from clinicMRI, TMS and EEG, and behavioral tasks and surveys online.
Primary Outcome Measure
Feasibility for all aspects of the study [ Time Frame: 1-7 days ]
Central Contacts
- David Darrow(612) 624-6666
- MATTHEW D Maple612-946-1424
Locations (1)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| University of Minnesota | Minneapolis | Minnesota | 55455 |
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