Transdiagnostic Cognitive Biomarkers

Part of paid clinical trials in Minneapolis, Minnesota.

Sponsor
University of Minnesota
Study ID
NCT04864080
Status
Recruiting

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • Computer game/task — BEHAVIORAL
    N-back, COGED, PacMan game, Bandit task, Websurf task.
  • Health surveys online — BEHAVIORAL
    Health surveys to study themes like pain, sleep, depression and anxiety, and PTSD.

Study Details

The overall objective of this study is to determine the feasibility of identifying transdiagnostic biomarkers of cognitive function mediated by neuromodulation of the dorsolateral prefrontal cortex that are translatable across disease groups in order to more accurately phenotype clusters of cognitive dysfunction. Completing behavioral paradigms with electrophysiology and TMS is a challenging frontier. This study focuses on the feasibility of such an endeavor for those with chronic pain or depression as well as healthy controls.

Key Dates

Start date
Apr 11, 2022
Status verified
Mar 2026
Primary completion
Mar 1, 2027
Completion
Mar 1, 2027

Study Design

Enrollment
45 participants (estimated)
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC

Arms

  • Active Comparator: Healthy Comparison Group
    Behavioral tasks and surveys online.
  • Experimental: Pain/Depression patients from clinic
    MRI, TMS and EEG, and behavioral tasks and surveys online.

Primary Outcome Measure

Feasibility for all aspects of the study [ Time Frame: 1-7 days ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of MinnesotaMinneapolisMinnesota55455
David Darrow
612-946-1424

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