Changes in Microbial Status From Dentate, Edentulous and After Dental Implant Placement

Part of paid clinical trials in Cleveland, Ohio.

Sponsor
Case Western Reserve University
Study ID
NCT06149585
Status
Recruiting
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Conditions

  • Edentulous Mouth
  • Microbial Colonization
  • Periodontal Diseases
  • Periodontitis, Adult

Eligibility Criteria

Sex
ALL
Age
21 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • Microbial Sampling — OTHER
    Pool microbial sampling will be performed and changes in the microbiome will be evaluated and compared for differences

Study Details

The objectives of this study are to analyze the oral microbiome modulations occurring during the transition from partial (with some residual teeth) to full edentulous (without remaining teeth) status and implant placement in subjects affected by severe periodontitis; to evaluate if microbiome changes in relation to the used of different implant material/surface; and to assess the variance of the changes to determine the sample size for future longitudinal prospective studies.

Key Dates

Start date
Aug 16, 2023
Status verified
Jun 2025
Primary completion
May 1, 2026
Completion
May 1, 2027

Study Design

Enrollment
12 participants (estimated)

Arms

  • Arm: Intra-Lock Fusion Implants
    These patients will receive Intra-Lock Fusion Implants during implant placement
  • Arm: Tapered Pro Implants
    These patients will receive Tapered Pro Implants during implant placement

Primary Outcome Measure

Oral microbiome composition changes in patients who are dentate, edentulous, and have dental implants [ Time Frame: Through study completion, an average of 24 months ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Case Western Reserve University Department of PeriodonticsClevelandOhio44106
Gian Pietro Schincaglia, DDS, PhD
[email protected]
216-368-4412
Elysha Pomerantz, DMD
[email protected]
216-368-4412

Find similar trials in Cleveland, OH

By research site
Case Western Reserve University Department of Periodontics· Cleveland, OH

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