The Influence of Aerobic Exercise on Consolidation of Fear Extinction Learning in PTSD

Part of paid clinical trials in Tuscaloosa, Alabama.

Sponsor
University of Alabama, Tuscaloosa
Study ID
NCT06144203
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 64 Years
Healthy Volunteers
Accepted

Interventions

  • Exercise — BEHAVIORAL
    Participants will complete either a 30-minute bout of light-, moderate-, or high-intensity aerobic exercise at one of the visits.

Study Details

This study aims to test whether aerobic exercise performed after fear extinction learning improves cognitive, physiological, and neural indices of extinction recall in a sample of trauma-exposed men and women with and without posttraumatic stress disorder (PTSD). Participants will complete a clinical intake visit (Day 0), followed by a three-day fear conditioning (day 1), fear extinction + activity (day 2), and fear extinction recall (day 3) protocol.

Key Dates

Start date
Jan 29, 2024
Status verified
Feb 2024
Primary completion
Mar 31, 2029
Completion
Mar 31, 2029

Study Design

Enrollment
120 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE

Arms

  • Experimental: Light-intensity aerobic exercise
  • Experimental: Moderate-intensity aerobic exercise
  • Experimental: High-intensity aerobic exercise

Primary Outcome Measure

Skin conductance responses [ Time Frame: Collected during fear conditioning, fear extinction, and extinction recall task. ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Wade Hall - University of AlabamaTuscaloosaAlabama35487
Kevin Crombie, PhD
[email protected]
205-348-2684

Find similar trials in Tuscaloosa, AL

By condition
PTSD (post-traumatic stress disorder)
By specialty
PsychiatryMental healthBehavioral health
By research site
Wade Hall - University of Alabama· Tuscaloosa, AL

Related Studies