Endurance Exercise & Virtual Reality for Optimizing Cortical Excitability and Neuroplasticity in PD

Part of paid clinical trials in San Antonio, Texas.

Sponsor
The University of Texas Health Science Center at San Antonio
Study ID
NCT06133283
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 85 Years
Healthy Volunteers
Not accepted

Interventions

  • High intensity endurance exercise — BEHAVIORAL
    High intensity interval exercise on a recumbent stepper for 30 minutes, 3 days per week.
  • Stretching exercise — BEHAVIORAL
    Stretches of face, neck, upper extremity, trunk and lower extremity muscles including whole body stretches for 30 minutes, 3 days per week.
  • Virtual reality (VR)-based gaming — BEHAVIORAL
    VR games will involve games that challenge balance such as reaching different targets during activities such as sit to stand, dodging obstacles etc. Participants will play approximately 6 games for 30 minutes, 3 days a week.

Study Details

This study aims to determine the effects of aerobic exercise as a primer to add-on virtual reality (VR)-based rehabilitation on balance, postural control and neuroplasticity (ability of brain to adapt in structure and function) in individuals with Parkinson's disease (PD). This study will utilize two groups - one group will receive the exercise and VR, while the other group will receive stretching exercise and VR over eight weeks. The study team will administer outcomes at baseline, post-intervention (8 weeks) and follow-up (6 weeks after post-assessment).

Key Dates

Start date
Feb 9, 2024
Status verified
Mar 2026
Primary completion
Dec 31, 2026
Completion
Dec 31, 2026

Study Design

Enrollment
16 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: High intensity endurance exercise and virtual reality (experimental)
    The exercise group will perform high intensity interval exercise and VR-based games 3 times a week for 8 weeks.
  • Other: Stretching and virtual reality (control)
    The stretching group will perform stretching exercises and VR-based games 3 times a week for 8 weeks.

Primary Outcome Measure

Balance [ Time Frame: Baseline, post (8 week), follow-up (14 weeks) ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
UT Health San Antonio- Dept. of Physical TherapySan AntonioTexas78229
Anjali Sivaramakrishnan, PT, PhD
[email protected]
210-567-8626

Find similar trials in San Antonio, TX

By condition
Parkinson's disease
By specialty
NeurologyBrain disorders
By research site
UT Health San Antonio- Dept. of Physical Therapy· San Antonio, TX

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