Guided Episodic Future Thinking to Increase Physical Activity Adherence and Promote Healthy Brain Aging

Part of paid clinical trials in Kansas City, Kansas.

Sponsor
University of Kansas Medical Center
Study ID
NCT06123182
Status
Recruiting
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Conditions

  • Aging
  • Exercise Training

Eligibility Criteria

Sex
ALL
Age
45 Years - 65 Years
Healthy Volunteers
Accepted

Interventions

  • Episodic Future Thinking — BEHAVIORAL
    During the audio recorded guided imagery exercise participants will be asked to think in detail of a future (6 months to a year) where they have made healthy choices regarding physical activity and are physically active.
  • Episodic Recent Thinking — BEHAVIORAL
    During the audio recorded guided imagery exercise participants will be asked to think about a routine weekly activity.
  • Positive Affective Imagery — BEHAVIORAL
    During the audio recorded guided imagery exercise participants will be asked to think in detail about the positive outcomes and sensations associated with an exercise bout.
  • Neutral Affective Imagery — BEHAVIORAL
    During the audio recorded guided imagery exercise participants will be asked to think in detail about the physical sensations associated with an exercise bout.
  • HIIT Exercise Intervention — BEHAVIORAL
    The high intensity interval training (HIIT) will be conducted 2 times per week for 6 weeks. The duration of each individual exercise session will last about 45 minutes. After the 5-minute warm-up at 30% peak workload, HIIT will consist of repeated 1-minute high intensity bursts ("on" interval) alternated with 1-minute interval recovery ("off" interval) for 25 minutes. The "on" interval will begin at 80% of peak watts (range: 75%-85%) followed by the "off" interval at 10% of peak watts. The session will end with up to 10 minute cool-down at 20% peak workload.

Study Details

The goal of this behavioral clinical trial is to learn how to increase physical activity in mid-life adults. Specifically, can guided imagery that includes creating mental pictures increase excitement about working out. Participants will be asked to complete testing at the beginning of the study, following 6-weeks of an in-person exercise program, and 6-weeks after finishing the exercise program. Testing will include an exercise test, MRI, questionnaires, computer tasks, and a blood draw.

Key Dates

Start date
Feb 23, 2024
Status verified
Mar 2026
Primary completion
May 31, 2027
Completion
May 31, 2027

Study Design

Enrollment
160 participants (estimated)
Allocation
RANDOMIZED
Intervention model
FACTORIAL
Primary purpose
PREVENTION

Arms

  • Experimental: Episodic Future Thinking (EFT) + Positive Affective Imagery (PAI)
    Assigned guided imagery will be delivered during each exercise session throughout the 6-week exercise program. The guided imagery recordings will be delivered via audio recording during warm-up and cool-down periods during in-lab exercise sessions. The EFT will always be delivered during warm-up and the PAI will always be delivered during cool-down.
  • Experimental: Episodic Future Thinking (EFT) + Neutral Affective Imagery (NAI)
    Assigned guided imagery will be delivered during each exercise session throughout the 6-week exercise program. The guided imagery recordings will be delivered via audio recording during warm-up and cool-down periods during in-lab exercise sessions. The EFT will always be delivered during warm-up and the NAI will always be delivered during cool-down.
  • Experimental: Episodic Recent Thinking (ERT) + Positive Affective Imagery (PAI)
    Assigned guided imagery will be delivered during each exercise session throughout the 6-week exercise program. The guided imagery recordings will be delivered via audio recording during warm-up and cool-down periods during in-lab exercise sessions. The ERT will always be delivered during warm-up and the PAI will always be delivered during cool-down.
  • Active Comparator: Episodic Recent Thinking (ERT) + Neutral Affective Imagery (NAI)
    Assigned guided imagery will be delivered during each exercise session throughout the 6-week exercise program. The guided imagery recordings will be delivered via audio recording during warm-up and cool-down periods during in-lab exercise sessions. The ERT will always be delivered during warm-up and the NAI will always be delivered during cool-down.

Primary Outcome Measure

Adherence to HIIT exercise [ Time Frame: 1 to 6-weeks ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of Kansas Medical CenterKansas CityKansas66160
Morgan Brucks, B.A.
(913) 588-0173

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By research site
University of Kansas Medical Center· Kansas City, KS

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