LiverPAL: A Trial of Inpatient Palliative Care for Patients With Advanced Liver Disease

Part of paid clinical trials in Boston, Massachusetts.

Sponsor
Massachusetts General Hospital
Study ID
NCT05998330
Status
Recruiting
Apply to this trial

Conditions

  • Advanced Cirrhosis
  • Cirrhosis
  • Cirrhosis, Liver
  • End Stage Liver DIsease
  • Liver Disease Chronic

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • LiverPAL — BEHAVIORAL
    The intervention include integrating early palliative care with usual hepatology care to evaluate and treat patients' symptoms, enhance their illness and prognostic understanding, support their coping, and coordinate their serious illness, transitional, and end-of-life care.

Study Details

The goal of this clinical trial is to evaluate whether early integration of palliative care in the care of hospitalized patients with advanced liver disease (AdvLD) can improve patients' quality of life, physical symptoms, mood, and serious illness communication. Palliative care is a medical specialty focused on lessening (or "palliating") symptoms and assisting in coping with serious illness.

Key Dates

Start date
Sep 20, 2023
Status verified
Jul 2025
Primary completion
Jul 31, 2027
Completion
Jul 31, 2027

Study Design

Enrollment
200 participants (estimated)
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
SUPPORTIVE_CARE

Arms

  • No Intervention: Usual Hepatology Care
    Usual hepatology care
  • Experimental: Usual Hepatology Care with Early Palliative Care
    Usual hepatology care with early palliative care

Primary Outcome Measure

Patient Quality of Life (Functional Assessment of Chronic Illness Therapy - Palliative Care, FACIT-Pal) up t0 4 weeks [ Time Frame: Up to 4 weeks ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Massachusetts General HospitalBostonMassachusetts02114
Grace Bizup, BA
[email protected]
617-724-1316
Will Munroe, BA
[email protected]
617- 726-0161
Nneka N Ufere, MD MSCE (PRINCIPAL_INVESTIGATOR)

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By research site
Massachusetts General Hospital· Boston, MA

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