Episodic Memory Integration and Interference

Part of paid clinical trials in Chestnut Hill, Massachusetts.

Sponsor
Boston College
Study ID
NCT05974371
Status
Not Yet Recruiting

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Conditions

  • Episodic Memory

Eligibility Criteria

Sex
ALL
Age
18 Years - 39 Years
Healthy Volunteers
Accepted

Interventions

  • emotional context similarity — OTHER
    On Day 1, all participants will encode AB neutral word pairs (e.g., Pencil - Car) shown with positive, negative, or neutral images. On Day 2, all participants will encode AC neutral words pairs (e.g., Pencil - Book) alongside images of either the same or different valence. The emotional similarity of AB (Day 1) and AC (Day 2) image contexts (i.e., the independent variable) will consist of the following conditions: positive-positive, positive-negative, negative-negative, negative-positive, neutral-neutral, neutral-positive, and neutral-negative.

Study Details

The purpose of this study is to assess how emotional memories integrate and interfere with one another over time. We will be using a multi-session experimental paradigm consisting of two encoding sessions and one retrieval session. Participants will either complete these sessions online or in-person, with the latter collecting functional magnetic resonance imaging during the two encoding sessions.

Key Dates

Start date
Aug 31, 2024
Status verified
Jul 2023
Primary completion
Aug 31, 2027
Completion
Aug 31, 2027

Study Design

Enrollment
150 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE

Arms

  • Experimental: Emotional memory updating paradigm
    All participants will encode AB/AC word pairs shown with images that have differing emotional valence (positive, negative, or neutral)

Primary Outcome Measure

Memory for the Associated Words [ Time Frame: Day 3 ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Boston CollegeChestnut HillMassachusetts02467
Elizabeth Kensinger
617-552-1350

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