Point of Care Lung Ultrasound in Preterm Infants With Respiratory Distress

Part of paid clinical trials in Phoenix, Arizona.

Sponsor
Phoenix Children's Hospital
Study ID
NCT05925075
Status
Enrolling By Invitation

Conditions

  • Bronchopulmonary Dysplasia

Eligibility Criteria

Sex
ALL
Age
0 Days - N/A
Healthy Volunteers
Not accepted

Interventions

  • Lung Ultrasound — DIAGNOSTIC_TEST
    Lung ultrasound to be performed at scheduled intervals as described in individual cohorts.

Study Details

The goal of this observational study is to learn about the role of bedside lung ultrasound in infants born prematurely with breathing problems. The main question this study aims to answer is: Can bedside lung ultrasound performed in the first month of life predict the development of chronic lung disease in premature infants?

Key Dates

Start date
Apr 17, 2023
Status verified
May 2026
Primary completion
Jun 24, 2027
Completion
Jun 24, 2027

Study Design

Enrollment
150 participants (estimated)

Arms

  • Arm: RDS
    Infant born less than 32 weeks gestation with diagnosis of respiratory distress syndrome. Lung ultrasounds will be performed on day of life 7, 14, 21, 28 and at corrected gestational age of 36 weeks.
  • Arm: PDA
    In addition to being less than 32 weeks gestation, subject can qualify for study and receive a lung ultrasound scan at time of echo diagnosis of patent ductus arteriosus (PDA).
  • Arm: Steroid
    Aims are : A: To evaluate changes in LUS scores pre and post treatment with systemic steroid course. B: To evaluate the predictive ability of LUS for successful extubation following course of systemic steroids. Lung ultrasound scans will be done prior to initiation of post-natal steroid, day 1, day 3, day 7, day 10 of treatment and 1 week after steroid is discontinued.

Primary Outcome Measure

Assess predictive ability of lung ultrasound scores in infants at risk of developing bronchopulmonary dysplasia (BPD) [ Time Frame: The lung ultrasounds will be performed on day of life 7, 14, 21 and 28 and diagnosis of BPD would be per standard criteria. ]

Locations (1)

FacilityCityStateZIPSite coordinators
Phoenix Children'sPhoenixArizona85016-

Find similar trials in Phoenix, AZ

By research site
Phoenix Children's· Phoenix, AZ

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