Training Response Artificial Intelligence Network (TRAIN)

Part of paid clinical trials in Gainesville, Florida.

Sponsor
University of Florida
Study ID
NCT05903573
Status
Recruiting
Apply to this trial

Conditions

  • Amnestic Mild Cognitive Impairment

Eligibility Criteria

Sex
ALL
Age
55 Years - 100 Years
Healthy Volunteers
Not accepted

Interventions

  • Cognitive Training — BEHAVIORAL
    The intervention group will receive cognitive training that provides specific training tasks directed at essential cognitive domains tied to the project's aims and hypotheses (processing speed and working memory) that correspond with the neurocognitive and functional neuroimaging measures to be studied.
  • Computerized Cognitive Stimulation — BEHAVIORAL
    Participants will complete cognitively-stimulating computer activities. The duration is 60 min/day; the frequency is two to three days/wk, for 16 weeks with the goal of completing 40 sessions.

Study Details

This study will train a machine learning tool to predict response to a cognitive training intervention using baseline brain MRI sequences from older adults with amnestic mild cognitive impairment.

Key Dates

Start date
Oct 9, 2023
Status verified
Dec 2025
Primary completion
Apr 30, 2028
Completion
Apr 30, 2028

Study Design

Enrollment
75 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Intervention Group: Cognitive Training
    Participants will complete computerized cognitive training via Posit Science Brain HQ. The duration is 60 min/day; the frequency is two to three days/wk, for 16 weeks with the goal of completing 40 sessions.
  • Active Comparator: Active Control Group: Computerized Cognitive Stimulation
    Participants will complete cognitively-stimulating computer activities. The duration is 60 min/day; the frequency is two to three days/wk, for 16 weeks with the goal of completing 40 sessions.

Primary Outcome Measure

Useful Field of View Composite [ Time Frame: Baseline up to week 12 during follow-up ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of FloridaGainesvilleFlorida32610
Joseph Gullett, PhD
[email protected]
352-294-8631
Joseph M Gullett, PhD (PRINCIPAL_INVESTIGATOR)

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By research site
University of Florida· Gainesville, FL

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