Characterizing Variability in Hearing Aid Outcomes in Among Older Adults With Alzheimer's Dementia

Part of paid clinical trials in Chicago, Illinois.

Sponsor
Northwestern University
Study ID
NCT04240561
Status
Recruiting
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Conditions

  • Amnestic Mild Cognitive Impairment
  • Dementia of Alzheimer Type
  • Hearing Loss, Sensorineural

Eligibility Criteria

Sex
ALL
Age
50 Years - 90 Years
Healthy Volunteers
Not accepted

Interventions

  • High level of signal manipulation — DEVICE
    Hearing aid will be programmed to a high level of signal manipulation.
  • Low level of signal manipulation — DEVICE
    Hearing aid will be programmed to a low level of signal manipulation.

Study Details

This current translational project, funded by NIH, aims to better understand the impact of various signal modification strategies for older adults with Alzheimer's dementia and its potential precursor, known as amnestic mild cognitive impairment. The investigators hypothesize that adults with Alzheimer's dementia represent an extreme case of restricted cognitive ability, such that very low working memory capacity and overall reduced cognitive capacity will limit benefit from advanced signal processing. Thus, the investigators hypothesize that adults with Alzheimer's dementia will receive greater benefit from acoustically simple, high-fidelity hearing aid processing that minimally alters the acoustic signal.

Key Dates

Start date
Jul 1, 2021
Status verified
Apr 2026
Primary completion
Aug 31, 2027
Completion
Aug 31, 2027

Study Design

Enrollment
20 participants (estimated)
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT

Arms

  • Experimental: Hearing Aid Fitting Order A
    Participants wear hearing aids with a high level of signal manipulation, followed by a low level of signal manipulation
  • Experimental: Hearing Aid Fitting Order B
    Participants wear hearing aids with a low level of signal manipulation, followed by a high level of signal manipulation

Primary Outcome Measure

Change In Speech Intelligibility (%Correct) [ Time Frame: Change from Baseline to final appointment ineach hearing aid condition will be assessed. Participants will take an unaided baseline at the start of the trial. Measure will be repeated at the end of each intervention (3-5 weeks after each fitting). ]

Central Contacts

Locations (2)

FacilityCityStateZIPSite coordinators
Northwestern UniversityChicagoIllinois60611
Kendra Marks, AuD
[email protected]
8474670897
Northwestern UniversityEvanstonIllinois60208
Kendra Marks
[email protected]
847-467-0897

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