Low-Intensity Mechanical Stimulation for Hematologic Malignancy Patients

Part of paid clinical trials in Buffalo, New York.

Sponsor
Roswell Park Cancer Institute
Study ID
NCT05893940
Status
Recruiting
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Conditions

  • Hematopoietic and Lymphoid System Neoplasm

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Low Intensity Vibration Therapy — PROCEDURE
    Undergo LIMS vibration therapy
  • Dual X-ray Absorptiometry — PROCEDURE
    Undergo DEXA scan
  • Biospecimen Collection — PROCEDURE
    Undergo blood sample collection

Study Details

This clinical trial tests the effect of low-intensity mechanical stimulation (LIMS) vibration therapy in patients with hematologic malignancies. Patients with hematologic malignancies often undergo a blood and/or bone marrow transplant (hematopoietic cell transplantation \[HCT\]) or cellular therapy. The LIMS board delivers vibrations through the bones that may stimulate bone growth and may also increase muscle activity and strength and may also increase T-cell activation in patients planning to undergo cellular therapy. LIMS vibration therapy may stop or reverse BMD loss and/or improve the development of T-cells in the body in patients with hematologic malignancies who are undergoing or may plan to undergo HCT or cellular therapies.

Key Dates

Start date
Aug 14, 2023
Status verified
Dec 2025
Primary completion
Sep 1, 2026
Completion
Sep 1, 2026

Study Design

Enrollment
75 participants (estimated)
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION

Arms

  • Experimental: LIMS vibration Therapy, DEXA Scan - Cohort 1
    Patients undergo LIMS vibration therapy over 10 minutes on study. Patients also undergo DEXA scan at follow up and may optionally undergo blood sample collection and questionnaire at baseline and follow up
  • Experimental: LIMS vibration therapy - Cohort II
    Patients undergo LIMS vibration therapy over 10-minutes BID for 14 days on study. Patients also undergo blood sample collection throughout the trial.

Primary Outcome Measure

time spent on LIMS - Cohort I [ Time Frame: Up to 120 days post hematopoietic cell transplantation (HCT) ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Roswell Park Comprehensive Cancer CenterBuffaloNew York14263
Megan Herr, MD
[email protected]
877-275-7724

Find similar trials in Buffalo, NY

By research site
Roswell Park Comprehensive Cancer Center· Buffalo, NY

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