Identifying and Caring for Individuals With Inherited Cancer Syndrome

Part of paid clinical trials in Portland, Oregon.

Sponsor
OHSU Knight Cancer Institute
Study ID
NCT04494945
Status
Recruiting
Apply to this trial

Conditions

  • BRCA1/2-Associated Hereditary Breast and Ovarian Cancer Syndrome
  • Breast Ductal Carcinoma In Situ
  • Hematopoietic and Lymphoid System Neoplasm
  • Hereditary Neoplastic Syndrome
  • Lynch Syndrome
  • Malignant Solid Neoplasm

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • Biospecimen Collection — PROCEDURE
    Undergo collection of saliva sample
  • Genetic Counseling — OTHER
    Receive genetic counseling if testing results are positive
  • Genetic Testing — OTHER
    Undergo genetic testing
  • Survey Administration — OTHER
    Complete a survey

Study Details

This trial examines approaches to identify and care for individuals with inherited cancer syndrome. The purpose of this study is to offer no cost genetic testing to the general public. Researchers hope to learn the value of providing broad, public-wide testing for high risk cancer types (like hereditary breast and ovarian cancer or Lynch syndromes) instead of only testing people whose families are known to be high risk.

Key Dates

Start date
Mar 9, 2020
Status verified
Jan 2026
Primary completion
Mar 31, 2026
Completion
Mar 31, 2026

Study Design

Enrollment
27,500 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SCREENING

Arms

  • Other: Screening (genetic testing)
    Patients undergo collection of saliva samples for genetic testing. If genetic test is positive, patients receive genetic counseling.

Primary Outcome Measure

Effectiveness and sustainability of heritable cancer syndrome testing in the two novel testing populations [ Time Frame: Up to 5 years ]

Locations (2)

FacilityCityStateZIPSite coordinators
OHSU Knight Cancer InstitutePortlandOregon97239
Jackilen Shannon, Ph.D.
[email protected]
503-494-4993
Jackilen Shannon, Ph.D. (PRINCIPAL_INVESTIGATOR)
Providence Portland Medical CenterPortlandOregon97213
Bill J. Wright, Ph.D.
[email protected]
Bill J. Wright, Ph.D. (PRINCIPAL_INVESTIGATOR)

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By research site
OHSU Knight Cancer Institute· Portland, ORProvidence Portland Medical Center· Portland, OR

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