Targeted Motor Learning to Improve Gait for Individuals With Parkinson Disease

Part of paid clinical trials in Chapel Hill, North Carolina.

Sponsor
University of North Carolina, Chapel Hill
Study ID
NCT05864157
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
50 Years - 80 Years
Healthy Volunteers
Not accepted

Interventions

  • Gait training without rhythmic auditory cues — OTHER
    Gait training on treadmill and overground without any rhythmic auditory cues
  • TRAC — OTHER
    Metronome set to 85% on treadmill and 115% when walking overground
  • dTRAC — OTHER
    Metronome set around 85% on treadmill and around 115% when walking overground

Study Details

The purpose of this research study is to determine how training to step with a metronome on both a treadmill, as well as overground, will influence the way that people with Parkinson disease walk. Using metronomes is commonly used in clinics, but the investigators will be using a combination of slow and fast frequencies to alter the way that people walk. The use of a slower frequency metronome on the treadmill is intended to help participants take larger steps. The use of a faster frequency metronome while walking overground is intended to help participants take faster steps.This will take place over 12 training sessions. Each session will be about an hour. It will include some walking tests and pictures of the brain (using MRI) before and after training.

Key Dates

Start date
Aug 16, 2023
Status verified
Nov 2025
Primary completion
May 1, 2026
Completion
May 3, 2026

Study Design

Enrollment
45 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Active Comparator: Control
    Participants will perform walking practice on a treadmill and overground without the use of a metronome.
  • Experimental: Targeted Rhythmic Auditory Cueing (TRAC)
    Participants will perform walking practice on a treadmill (with a metronome set to 85% of typical cadence) and overground (with a metronome set to 115% of typical cadence).
  • Experimental: Distorted Targeted Rhythmic Auditory Cueing (dTRAC)
    Participants will perform walking practice on a treadmill (with a metronome set around 85% of typical cadence) and overground (with a metronome set around 115% of typical cadence).

Primary Outcome Measure

Change in Six minute walk test (6MWT) at the 3 month follow up visit [ Time Frame: Baseline, 3 month follow-up ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of North Carolina at Chapel HillChapel HillNorth Carolina27599
Michael Lewek, PT, PhD

Find similar trials in Chapel Hill, NC

By condition
Parkinson's disease
By specialty
NeurologyBrain disorders
By research site
University of North Carolina at Chapel Hill· Chapel Hill, NC

Related Studies