Total Intravenous Anesthesia (TIVA)/Sevoflurane Initiated Intravenous Anesthesia (SIIVA) in Pediatric Patients

Part of paid clinical trials in Winston-Salem, North Carolina.

Sponsor
Wake Forest University Health Sciences
Study ID
NCT05837936
Status
Recruiting
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Conditions

  • Extubation

Eligibility Criteria

Sex
ALL
Age
N/A - 9 Years
Healthy Volunteers
Not accepted

Interventions

  • Total intravenous anesthesia (TIVA) — OTHER
    TIVA anesthetic -no inhalational gases for surgery
  • Sevoflurane initiated intravenous anesthesia (SIIVA) — OTHER
    SIIVA - sevoflurane anesthetic gases for surgery

Study Details

Because Propofol is the primary "anesthetic agent," and inhalational agents remain in trace quantities at the end of the procedure Sevoflurane initiated intravenous anesthesia (SIIVA) or not present at all Total intravenous anesthesia (TIVA) it is likely that different criteria may be predictive of extubation success in these patients compared to inhalational anesthesia.

Key Dates

Start date
Mar 28, 2023
Status verified
Dec 2025
Primary completion
Mar 31, 2028
Completion
Mar 31, 2028

Study Design

Enrollment
600 participants (estimated)

Arms

  • Arm: Total intravenous anesthesia (TIVA)
    TIVA is achieved without inhalational agents and may be performed in cases where patients have an intravenous line in place prior to induction of anesthesia
  • Arm: Sevoflurane initiated intravenous anesthesia (SIIVA)
    SIIVA is a modification of TIVA in the setting where a patient does not tolerate the insertion of an intravenous line prior to induction of anesthesia. The patient undergoes induction of anesthesia with sevoflurane and transition to Propofol IV anesthesia for maintenance once the intravenous line is in place and discontinues the inhalational agent, sevoflurane.

Primary Outcome Measure

Extubation success rate [ Time Frame: Day 1 ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Atrium Health Wake Forest BaptistWinston-SalemNorth Carolina27157
Thomas "Wes" Templeton, MD
[email protected]
336-716-4498
Lynnette C Harris, BSN
[email protected]
336-716-8791
Thomas "Wes" Templeton, MD (PRINCIPAL_INVESTIGATOR)

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By research site
Atrium Health Wake Forest Baptist· Winston-Salem, NC

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