Simultaneous Prospective Kidney Transplant Assessment in Combined Liver Kidney Candidates

Part of paid clinical trials in Indianapolis, Indiana.

Sponsor
Indiana University
Study ID
NCT05717842
Status
Recruiting
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Conditions

  • Transplant

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Nuclear Medicine Scan — RADIATION
    Mercaptoacetyltriglycine 3 (Mag 3) Nuclear Medicine Scan

Study Details

The purpose of the study is to determine how much a persons kidney function recovers after receiving a simultaneous liver kidney transplant. The investigators will be contacting patients with kidney dysfunction with estimated GFR between 25 and 40 (not on dialysis treatment) who are listed to receive a simultaneous liver kidney (SLK) transplant to look at this function recovery. The investigators hope to develop a criteria based on GFR measurement, kidney function calculations from native kidneys vs transplanted kidney and compare the contributions, and correlate with estimated GFR on basic metabolic panel (BMP: a blood test) to predict higher chances of recovery of native kidney function.

Key Dates

Start date
Dec 8, 2023
Status verified
Mar 2026
Primary completion
Dec 31, 2026
Completion
Feb 28, 2027

Study Design

Enrollment
15 participants (estimated)

Arms

  • Arm: People with ESLD and eGFR between >=25 and <=40ml/min
    1. \> 18 years old 2. Listed for Liver Transplant for ESLD and Kidney Transplant (not on dialysis) 3. Candidates with two native kidneys. 4. Willing to participate and sign informed consent

Primary Outcome Measure

perform a nuclear medicine scan prior to SLK transplant [ Time Frame: up to 100 weeks ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
IU Health University HospitalIndianapolisIndiana46202
Muhammad Y Jan (PRINCIPAL_INVESTIGATOR)

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By research site
IU Health University Hospital· Indianapolis, IN

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