Mitigation Efforts in Arsenic Exposure With Folic Acid Supplementation

Part of paid clinical trials in Birmingham, Alabama.

Sponsor: University of Alabama at Birmingham
Study ID: NCT05656664
Status: Enrolling By Invitation

Conditions

Arsenic and/or Arsenic Compound Adverse Reaction

Eligibility Criteria

Sex: ALL
Age: 18 Years - 89 Years
Healthy Volunteers: Accepted

Interventions

Folic Acid — DIETARY_SUPPLEMENT
Folic acid supplementation to assess for increased arsenic metabolite excretion
Placebo — OTHER
Placebo group to assess arsenic metabolite excretion

Study Details

The purpose of this study is to evaluate the effects on folic acid supplementation in a population living in an environment with chronic arsenic exposure in Birmingham, Alabama.

Key Dates

Start date: Sep 14, 2023
Status verified: Mar 2026
Primary completion: Dec 31, 2026
Completion: Dec 31, 2026

Study Design

Enrollment: 100 participants (estimated)
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: PREVENTION

Arms

Placebo Comparator: Placebo
Placebo daily 12 weeks
Experimental: Folic Acid
Folic acid 800 ug/day 12 weeks

Primary Outcome Measure

Measurement of urine and blood arsenic metabolites [ Time Frame: 12 weeks ]

Locations (1)

Facility	City	State	ZIP	Site coordinators
UAB Lung Health Center	Birmingham	Alabama	35205	-

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By research site

UAB Lung Health Center· Birmingham, AL