Influence of TMS on Attention Modulation

Part of paid clinical trials in Auburn, Alabama.

Sponsor
Auburn University
Study ID
NCT05611502
Status
Recruiting
Apply to this trial

Conditions

  • Drinking, Alcohol

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • TMS — DEVICE
    TMS will be administered in a pattern that is either excitatory or inhibitory.

Study Details

The purpose of this study is to help understand how attention processes influence brain engagement during emotion and social cognition. The investigators also want to know if these processes are associated with drinking alcohol. Participation includes three study visits of about 2 hours each over approximately a month. The first visit involves a magnetic resonance imaging (MRI) scan and answering survey questions. Each of the next two visits will involve a session of transcranial magnetic stimulation (TMS, a non-invasive brain stimulation technique) followed by another MRI scan. People in the Auburn/Opelika area 19 or older are eligible to participate. People who drink alcohol and people who do not drink or don't drink very much are invited to participate.

Key Dates

Start date
Aug 11, 2022
Status verified
Oct 2025
Primary completion
Dec 31, 2025
Completion
Dec 31, 2025

Study Design

Enrollment
40 participants (estimated)
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE

Arms

  • Experimental: TMS A
    TMS administered over right frontal eye field at 10 Hz, 110% of MT, 60 x 5 sec trains, 25 sec ITI
  • Active Comparator: TMS B
    TMS administered over right frontal eye field at 1 Hz, 110% of MT, 7 x 225 sec trains, 30 sec ITI

Primary Outcome Measure

Change in attention switching [ Time Frame: Baseline, immediately following TMS A, immediately following TMS B ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Auburn UniversityAuburnAlabama36849
SCAMPI Lab
[email protected]
334-521-2807
Samantha J Fede, PhD (PRINCIPAL_INVESTIGATOR)

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