The Natural History of TRPV4 Neuropathy

Part of paid clinical trials in Baltimore, Maryland.

Sponsor
Johns Hopkins University
Study ID
NCT05600764
Status
Recruiting

Conditions

  • TRPV4 Gene Mutation

Eligibility Criteria

Sex
ALL
Age
3 Years - 80 Years
Healthy Volunteers
Not accepted

Study Details

The goal of this research is to document the natural history of neuropathy in patients with a confirmed genetic mutation in the TRPV4 gene. The investigators are searching for patients willing to participate in a 6-year long study to document the symptoms of TRPV4-associated disease and their progression over time. Participation requires annual study visits at Johns Hopkins for adult and juvenile participants.

Key Dates

Start date
Dec 15, 2023
Status verified
Nov 2025
Primary completion
Dec 31, 2033
Completion
Dec 31, 2048

Study Design

Enrollment
70 participants (estimated)

Primary Outcome Measure

Tracking the severity of overall neuropathy symptoms [ Time Frame: Annually for 6 years ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Johns HopkinsBaltimoreMaryland21287
Betty Hu
410-502-2705

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