Investigating the Effects of Social Stress on Brain Imaging

Part of paid clinical trials in Cambridge, Massachusetts.

Sponsor
Massachusetts Institute of Technology
Study ID
NCT05591404
Status
Recruiting
Apply to this trial

Conditions

  • Social Stress

Eligibility Criteria

Sex
ALL
Age
18 Years - 55 Years
Healthy Volunteers
Accepted

Interventions

  • Trier Social Stress Test (TSST) — BEHAVIORAL
    Participants randomized to the TSST arm will experience the Trier Social Stress Test.

Study Details

The purpose of this study is to examine whether experiencing a social stressor prior to the collection of neuroimaging measures is associated with differences in brain activation in healthy participants.

Key Dates

Start date
Nov 17, 2025
Status verified
Nov 2025
Primary completion
Sep 30, 2026
Completion
Nov 30, 2026

Study Design

Enrollment
50 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER

Arms

  • Experimental: Film + TSST
    Nature Film + Trier Social Stress Test (TSST)
  • No Intervention: Film Only (No-TSST)
    Nature Film Only

Primary Outcome Measure

Differences in fMRI BOLD Response [ Time Frame: 45 minutes after TSST ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Massachusetts Institute of TechnologyCambridgeMassachusetts02139
Omar Rutledge, MS
[email protected]
617-324-2898
John Gabrieli, PhD (PRINCIPAL_INVESTIGATOR)

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By research site
Massachusetts Institute of Technology· Cambridge, MA