Longitudinal Prospective Study of Neurocognition & Neuroimaging in Primary BT Patients

Part of paid clinical trials in San Diego, California.

Sponsor
Jona Hattangadi-Gluth
Study ID
NCT05576103
Status
Recruiting
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Conditions

  • Glioma
  • Meningioma
  • Primary Brain Tumor
  • Schwannoma

Eligibility Criteria

Sex
ALL
Age
18 Years - 99 Years
Healthy Volunteers
Not accepted

Study Details

In this proposal, the investigators introduce a novel, translational study to prospectively examine primary brain tumor patients undergoing fractionated radiation therapy to the brain. Quantitative neuroimaging, radiation dose information, and directed neurocognitive testing will be acquired through this study to improve understanding of cognitive changes associated with radiation dosage to non-targeted tissue, and will provide the basis for evidence-based cognitive- sparing brain radiotherapy.

Key Dates

Start date
Jan 31, 2015
Status verified
Jun 2026
Primary completion
Dec 31, 2030
Completion
Dec 31, 2030

Study Design

Enrollment
300 participants (estimated)

Arms

  • Arm: Primary brain tumour patients receiving RT
    Primary brain tumor patients are screened at time of consultation for this observational study, and the study population is diverse across sex/gender, and racial/ethnic groups.

Primary Outcome Measure

Longitudinal changes in imaging biomarker volume (cc) from volumetric MR imaging [ Time Frame: baseline (pre-treatment), 3 months, 6 months, 12 months post-treatment ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Moores Cancer CenterSan DiegoCalifornia92037
Lara J Rose
[email protected]
858-822-6575
Jona Hattangadi-Gluth, MD

Find similar trials in San Diego, CA

By condition
Brain cancer
By specialty
OncologyNeuro-oncology
By research site
Moores Cancer Center· San Diego, CA

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