Hyperpolarized Imaging in Diagnosing Participants With Glioma

Part of paid clinical trials in San Francisco, California.

Sponsor
Susan Chang
Study ID
NCT03739411
Phase
PHASE1
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
19 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Hyperpolarized Carbon C 13 Pyruvate — RADIATION
    Given IV
  • Magnetic Resonance Imaging — PROCEDURE
    Undergo MRI
  • Radiation Therapy — RADIATION
    Undergo radiation therapy for cancer outside of this study.
  • Chemotherapy — DRUG
    Undergo chemotherapy for cancer outside of this study.

Study Details

This pilot trial studies the side effects of hyperpolarized carbon C 13 pyruvate magnetic resonance imaging (MRI) in diagnosing participants with glioma. Diagnostic procedures, such as hyperpolarized carbon C 13 pyruvate MRI, may help find and diagnose glioma.

Key Dates

Start date
Dec 9, 2015
Status verified
Mar 2026
Primary completion
Jun 1, 2028
Completion
Jun 1, 2028

Study Design

Enrollment
140 participants (estimated)
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC

Arms

  • Experimental: Cohort I (Hyperpolarized C13, MRI)
    Participants receive hyperpolarized carbon C 13 pyruvate intravenously IV and undergo MRI. The second hyperpolarized 13 C injection/imaging will be started approximately 15 to 60 minutes after the first injection for those who are willing to receive two 13 C injections
  • Experimental: Cohort II (Hyperpolarized C13, MRI)
    Participants receive hyperpolarized carbon C 13 pyruvate IV and undergo MRI before treatment and 4 weeks after completion of cancer therapy given outside of this study.

Primary Outcome Measure

Incidence of adverse events [ Time Frame: Up to 24 months ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of California, San FranciscoSan FranciscoCalifornia94143
Wendy Ma
[email protected]
(415) 514-4418
[email protected]
877-827-3222
Susan M. Chang, MD (PRINCIPAL_INVESTIGATOR)

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By specialty
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University of California, San Francisco· San Francisco, CA

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