Reducing Blood Pressure in Mid-life Adult Binge Drinkers

Part of paid clinical trials in Arlington, Texas.

Sponsor
The University of Texas at Arlington
Study ID
NCT05522075
Status
Recruiting
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Conditions

  • Aging
  • Alcohol Abstinence
  • Alcohol Drinking
  • Behavioral Problem
  • Binge Drinking
  • Blood Pressure
  • Lifestyle Factors
  • Vasodilation

Eligibility Criteria

Sex
ALL
Age
50 Years - 64 Years
Healthy Volunteers
Accepted

Interventions

  • Exercise Training — BEHAVIORAL
    Subjects will be asked to perform exercise training (high-intensity interval training) under supervision, 3 times per week for 8 weeks. Each training session will last 40 minutes and will consist of 10-minute warm up at 70% of maximal heart rate (HRmax), four 4-minute intervals at 90% of HRmax with 3-min active recovery at 70% of HRmax and 5-minute cool down at 70% of HRmax.
  • Alcohol Abstinence Intervention — BEHAVIORAL
    Subjects will be asked to abstain from alcohol for 8 weeks. Education materials and bi-weekly consultations will be provided.

Study Details

This study has two phases: Phase 1 is to examine blood pressure, microvascular function, and sympathetic nerve activity in mid-life adult binge drinkers vs. alcohol abstainers/moderate drinkers. Phase 2 is to examine the effect of 8-week aerobic exercise training on blood pressure, microvascular function, and sympathetic nerve activity in mid-life adult binge drinkers

Key Dates

Start date
Nov 21, 2022
Status verified
May 2026
Primary completion
Dec 31, 2026
Completion
Apr 30, 2027

Study Design

Enrollment
55 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION

Arms

  • Experimental: Exercise Group
    Binge drinkers who have been assigned to exercise group will receive baseline assessment, 8-week exercise training plus alcohol abstinence intervention, and post-intervention assessment.
  • Active Comparator: Non-exercise Group
    Binge drinkers who have been assigned to non-exercise group will receive baseline assessment, 8-week alcohol abstinence intervention, and post-intervention assessment.
  • No Intervention: Alcohol abstainer/moderate drinker group
    Alcohol abstainer/moderate drinker will complete baseline assessment only and will not receive any intervention.

Primary Outcome Measure

Feasibility of high-intensity interval training [ Time Frame: Through out the study participation (~3 months) ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of Texas at ArlingtonArlingtonTexas76010
Chueh-Lung Hwang, PhD, PT
[email protected]
817-272-9722

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