Decoding and Selective Modulation of Human Memory During Awake/Sleep Cycles

Part of paid clinical trials in Los Angeles, California.

Sponsor
University of California, Los Angeles
Study ID
NCT05452122
Status
Recruiting
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Conditions

  • Memory, Delayed

Eligibility Criteria

Sex
ALL
Age
18 Years - 65 Years
Healthy Volunteers
Not accepted

Interventions

  • Auditory and Electrical Stimulation — OTHER
    Electrical and auditory stimulation will be applied during sleep.

Study Details

The proposed project seeks to elucidate memory processes and consolidation during sleep by leveraging the unique capability of direct recordings from the human brain at multiple levels of resolution-single neurons, localized neuronal assemblies, intracranial local field potentials-during rich behavioral tasks with real-life narratives and extracting neural features that relate to different aspects of episodic experience. The investigators will further probe causal mechanisms of consolidation by application of auditory and electrical stimulations during sleep and its effect on modulating memory processes.

Key Dates

Start date
Jul 13, 2022
Status verified
Oct 2025
Primary completion
Aug 31, 2026
Completion
Aug 31, 2026

Study Design

Enrollment
150 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE

Primary Outcome Measure

Recognition Accuracy [ Time Frame: 1-2 days contained within the participants' 1-2 week hospital stay; Specifically for each experiment, the outcome measure will be computed during the pre- and post-sleep memory tasks ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of California Los AngelesLos AngelesCalifornia90095
Andreina Hampton
[email protected]
3236105293

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By research site
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