Neuroimaging Reveals Treatment-related Changes in DLD

Part of paid clinical trials in Cincinati, Ohio.

Sponsor
University of Cincinnati
Study ID
NCT05268341
Status
Recruiting
Apply to this trial

Conditions

  • Developmental Language Disorder

Eligibility Criteria

Sex
ALL
Age
48 Months - 71 Months
Healthy Volunteers
Accepted

Interventions

  • My Sentence Builder — BEHAVIORAL
    computer-assisted treatment program for expressive grammar

Study Details

Children with developmental language disorders (DLD, aka specific language impairment), a prevalent pediatric disorder, experience hallmark grammar deficits with life-long impacts on educational and occupational outcomes. While effective and early interventions can mitigate the impact of DLD, not enough is known about the neural basis of DLD in young children, yet is needed to inform the design of more individualized interventions. This project uses neuroimaging, along with behavioral methods, with the goal of better understanding the memory-language mechanisms that underlie grammar learning and impairment, while also considering their association to treatment-related changes in preschoolers with DLD.

Key Dates

Start date
May 24, 2022
Status verified
May 2026
Primary completion
Jun 30, 2027
Completion
Jun 30, 2027

Study Design

Enrollment
100 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Treatment
    computer assisted intervention targeting expressive grammar for preschoolers with DLD
  • No Intervention: No treatment
    business as usual classroom (educational) services

Primary Outcome Measure

Functional connectivity data (time 1) from typical and DLD preschoolers [ Time Frame: Time 1 (pre) ]

Central Contacts

Locations (6)

FacilityCityStateZIPSite coordinators
New Horizon ChildcareCincinatiOhio45207
Sherry Bell
[email protected]
513-861-5284
Cincinnati Children's HospitalCincinnatiOhio45229
Claire Miller, PhD
[email protected]
513-636-8409
CWFF CHild Development CenterCincinnatiOhio45229
Robin Brandy
[email protected]
513-569-5662
Empower Learn Create INCCincinnatiOhio45220
Sandy Paul
[email protected]
513-961-2825
Audrey Wilson
[email protected]
513-961-2825
University of CincinnatiCincinnatiOhio45267
Amber Yusko, MA
[email protected]
513-558-1416
Linda Roedig
[email protected]
513-558-8503
Wesley Education Center for Children and FamiliesCincinnatiOhio45229
Carla Butler
[email protected]
513-845-7990

Find similar trials in Cincinati, OH

By research site
New Horizon Childcare· Cincinati, OHCincinnati Children's Hospital· Cincinnati, OHCWFF CHild Development Center· Cincinnati, OHEmpower Learn Create INC· Cincinnati, OHUniversity of Cincinnati· Cincinnati, OHWesley Education Center for Children and Families· Cincinnati, OH

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