A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of Relatlimab Plus Nivolumab in Pediatric and Young Adults With Hodgkin and Non-Hodgkin Lymphoma

Part of paid clinical trials in Birmingham, Alabama.

Sponsor
Bristol-Myers Squibb
Study ID
NCT05255601
Phase
PHASE1/PHASE2
Status
Completed

Conditions

  • Hodgkin Disease
  • Lymphoma, Non-Hodgkin

Eligibility Criteria

Sex
ALL
Age
N/A - 30 Years
Healthy Volunteers
Not accepted

Interventions

  • Relatlimab — DRUG
    Specified Dose on Specified Days
  • Nivolumab — DRUG
    Specified Dose on Specified Days

Study Details

The purpose of this study is to assess the safety, tolerability, drug levels, and preliminary efficacy of relatlimab plus nivolumab in pediatric and young adult participants with recurrent or refractory classical Hodgkin lymphoma and non-Hodgkin lymphoma.

Key Dates

Start date
Sep 13, 2022
Status verified
Feb 2026
Primary completion
Dec 3, 2025
Completion
Dec 3, 2025

Study Design

Enrollment
5 participants (actual)
Allocation
NON_RANDOMIZED
Intervention model
SEQUENTIAL
Primary purpose
TREATMENT

Arms

  • Experimental: Relatlimab + Nivolumab

Primary Outcome Measure

Incidence of dose-limiting toxicities (DLTs) [ Time Frame: Up to 135 days following last dose ]

Locations (13)

FacilityCityStateZIPSite coordinators
Local Institution - 0077BirminghamAlabama35233-
Local Institution - 0024PhoenixArizona85016-
Local Institution - 0035Palo AltoCalifornia94304-
Local Institution - 0032New HavenConnecticut06510-
Local Institution - 0066Fort MyersFlorida33908-
Local Institution - 0073BaltimoreMaryland21287-
Local Institution - 0025MinneapolisMinnesota55454-
Local Institution - 0020JacksonMississippi39216-
Local Institution - 0071HackensackNew Jersey07601-
Local Institution - 0060New YorkNew York10032-
Local Institution - 0059ValhallaNew York10595-
Local Institution - 0029AustinTexas78723-
Local Institution - 0026San AntonioTexas78207-

Find similar trials in Birmingham, AL

By research site
Local Institution - 0077· Birmingham, ALLocal Institution - 0024· Phoenix, AZLocal Institution - 0035· Palo Alto, CALocal Institution - 0032· New Haven, CTLocal Institution - 0066· Fort Myers, FLLocal Institution - 0073· Baltimore, MD

Related Studies