The Effect of Interval Exercise on Functional Outcomes in Veterans With COPD and OSA

Part of paid clinical trials in Salem, Virginia.

Sponsor
VA Office of Research and Development
Study ID
NCT05254431
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
N/A - N/A
Healthy Volunteers
Not accepted

Interventions

  • Exercise — BEHAVIORAL
    Novel Moderate Intensity Interval Exercise The Experimental Design is a randomized trial of moderate intensity interval training (5-minute intervals at 50% VO2peak 3 times weekly for 12 weeks) in Veterans with COPD and OSA compared with standard of care controls

Study Details

The term "Overlap Syndrome" (OS) is used to describe the presence of both chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) in a single patient. Due to premature aging, patients with OS are prone to developing functional decline up to 20 years earlier than the general population. The International Classification of Functioning, Disability and Health (ICF) evaluates functional status in chronic pulmonary disease globally in 5 domains. The investigators propose to study validated outcomes in 3 of these domains: 1) participation in life situations; 2) physical activity; and 3) cardiovascular health. The investigators long-term goal is to develop an exercise strategy tailored to Veterans with OS which will reduce the risk of functional decline through increased PA.

Key Dates

Start date
Apr 1, 2022
Status verified
Apr 2026
Primary completion
Apr 1, 2027
Completion
Apr 1, 2027

Study Design

Enrollment
28 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER

Arms

  • Experimental: Exercise
    The Experimental Design is a randomized trial of Moderate intensity interval training (5-minute intervals at 50% VO2peak 3 times weekly for 12 weeks) in Veterans with COPD and OSA compared with standard of care controls
  • No Intervention: Usual Care
    Participants in the control group will be instructed to maintain their routine activity level for 12 weeks

Primary Outcome Measure

Scale number on Epworth Sleepiness Scale [ Time Frame: 12 weeks ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Salem VA Medical Center, Salem, VASalemVirginia24153-6404
Tracy A Hicks
[email protected]
540-982-2463
Donna J Arsura
[email protected]
(540) 982-2463
Madalina Macrea, MD PhD (PRINCIPAL_INVESTIGATOR)

Find similar trials in Salem, VA

By condition
COPD
By specialty
PulmonologyLung disease
By research site
Salem VA Medical Center, Salem, VA· Salem, VA

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