MS-ResearchBiomarkerS

Part of paid clinical trials in Los Angeles, California.

Sponsor
Cedars-Sinai Medical Center
Study ID
NCT05204459
Status
Recruiting
Apply to this trial

Conditions

  • Clinically Isolated Syndrome
  • Healthy Aging
  • Multiple Sclerosis
  • Multiple Sclerosis, Primary Progressive
  • Multiple Sclerosis, Relapsing-Remitting
  • Multiple Sclerosis, Secondary Progressive
  • Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease
  • Neurologic Autoimmune Disease
  • Neurologic Disorder
  • Neuromyelitis Optica Spectrum Disorders
  • Radiologically Isolated Syndrome

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Accepted

Study Details

This study is being conducted to investigate risk factors for disability progression in Multiple Sclerosis and related disorders (MSRD). The primary goal is to assess whether combining information from visual assessment, blood markers, as well as historical and ongoing longitudinal MRIs of the brain, orbit (the part of the skull where eyes are located), and/or spinal cord can predict changes in quantitative disability measures related to MSRD and neurological disease.

Key Dates

Start date
Nov 11, 2021
Status verified
Feb 2024
Primary completion
Nov 11, 2041
Completion
Nov 11, 2041

Study Design

Enrollment
1,000 participants (estimated)

Arms

  • Arm: RRMS, SPMS, PPMS, CIS or RIS
    Multiple Sclerosis (relapsing-remitting, primary or secondary progressive forms), clinically isolated syndrome, or radiologically isolated syndrome
  • Arm: NMOSD
    Neuromyelitis optica spectrum disorders
  • Arm: MOGAD
    Myelin oligodendrocyte glycoprotein antibody disorders
  • Arm: Neurological disorder other than MSRD
    Neurological disorders due to neurodegenerative, vascular, or headache conditions that are not related to multiple sclerosis or related disorders.
  • Arm: Healthy controls
    Healthy controls with no known neurological conditions

Primary Outcome Measure

Identifying risk factors for disability progression [ Time Frame: 10 years ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Cedars-Sinai Medical CenterLos AngelesCalifornia90048
Omar Al-Louzi, MD
[email protected]
310-423-4008
Group Neurology Research
[email protected]
(310)-423-6472

Find similar trials in Los Angeles, CA

By condition
Multiple sclerosis
By specialty
NeurologyBrain disordersAutoimmune disease
By research site
Cedars-Sinai Medical Center· Los Angeles, CA

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