Entire-body PET Scans for Multiple Sclerosis

Part of paid clinical trials in Ladera Ranch, California.

Sponsor
Brain Health Alliance
Study ID
NCT04390009
Phase
EARLY_PHASE1
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
25 Years - 55 Years
Healthy Volunteers
Accepted

Interventions

  • Entire-body PET-CT scans — DIAGNOSTIC_TEST
    Entire-body PET-CT scans will be performed with state-of-the-art scanners with different manufacturers' models including Siemens Biograph Vision, United Imaging uEXPLORER and possibly other recently FDA-approved PET-CT scanners.
  • Amyvid radiopharmaceutical — DRUG
    Amyvid (F18-florbetapir) will be evaluated for binding to white matter of the peripheral and central nervous system of participants

Study Details

To evaluate whether an entire-body positron emission tomography (PET) scanner can be exploited to improve evaluation, monitoring and measurement of both peripheral and central demyelination in multiple sclerosis (MS) patients.

Key Dates

Start date
Sep 30, 2024
Status verified
Jan 2025
Primary completion
Sep 30, 2025
Completion
Dec 30, 2025

Study Design

Enrollment
20 participants (estimated)
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC

Arms

  • Other: Siemens Biograph Vision PET-CT scans
    Parallel study arms defined by PET-CT scanners by different manufacturer and model
  • Other: United Imaging uEXPLORER PET-CT scans
    Parallel study arms defined by PET-CT scanners by different manufacturer and model

Primary Outcome Measure

Entire-body PET imaging of demyelination of peripheral and central nervous system [ Time Frame: During 1 day single PET-CT scan ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Brain Health AllianceLadera RanchCalifornia92694
Carl Taswell, MD, PhD
[email protected]
949-481-3121

Find similar trials in Ladera Ranch, CA

By condition
Multiple sclerosis
By specialty
NeurologyBrain disordersAutoimmune disease
By research site
Brain Health Alliance· Ladera Ranch, CA

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