Inspiratory Muscle Training in Obese Breast Cancer Survivors

Part of paid clinical trials in Columbus, Ohio.

Sponsor
Ohio State University Comprehensive Cancer Center
Study ID
NCT05193149
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
FEMALE
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Inspiratory muscle training — BEHAVIORAL
    Training of respiratory muscles
  • Exercise training — BEHAVIORAL
    Supervised aerobic exercise intervention

Study Details

The investigators propose a randomized controlled trial to determine the effectiveness of inspiratory muscle training in improving exercise tolerance among stage 0-III obese breast cancer survivors.

Key Dates

Start date
Nov 13, 2023
Status verified
Jan 2026
Primary completion
Jun 30, 2026
Completion
Jun 30, 2026

Study Design

Enrollment
78 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE

Arms

  • Experimental: 4 wk IMT + 12 wk exercise
    4 weeks of IMT, 3/week, 3 sets of 15 repetitions, intensity up to 70% of MIP using a pressure threshold device PLUS 12 weeks of aerobic exercise training including cycling, walking, elliptical, starting in week 5, 3/week, up to 50min per session, moderate intensity
  • Sham Comparator: 4 wk SHAM + 12 wk exercise
    4 weeks of SHAM training, 3/week, 3 sets of 15 repetitions, intensity up of 10% of MIP using a pressure threshold device PLUS 12 weeks of aerobic exercise training including cycling, walking, elliptical, starting in week 5, 3/week, up to 50min per session, moderate intensity

Primary Outcome Measure

Change in exercise tolerance [ Time Frame: Baseline to 4 weeks ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
The Ohio State UniversityColumbusOhio43210
Dharini M Bhammar, PhD
[email protected]
614-366-9467
Dharini M Bhammar, PhD (PRINCIPAL_INVESTIGATOR)
Sagar Sardesai, MD (PRINCIPAL_INVESTIGATOR)

Find similar trials in Columbus, OH

By condition
Breast cancerObesity / overweight
By specialty
OncologyBreast oncologyWomen's healthEndocrinologyMetabolic healthWeight loss
By research site
The Ohio State University· Columbus, OH

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