Lipoprotein Kinetics in T1D

Part of paid clinical trials in Columbia, Missouri.

Sponsor
University of Missouri-Columbia
Study ID
NCT05179954
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 45 Years
Healthy Volunteers
Accepted

Interventions

  • Metabolic testing — OTHER
    Participants will complete a metabolic testing protocol that includes intravenous infusion of stable isotope labeled tracers and blood sampling to determine lipoprotein kinetics

Study Details

The purpose of this research study is to understand how type 1 diabetes (T1D) increases the risk for cardiovascular diseases (heart attack and stroke). To this end, the investigators will compare apolipoprotein and triglyceride kinetics in people wtih T1D and healthy control participants.

Key Dates

Start date
May 9, 2022
Status verified
Feb 2026
Primary completion
Dec 31, 2026
Completion
Dec 31, 2027

Study Design

Enrollment
30 participants (estimated)
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE

Arms

  • Other: Control group
    Healthy control group
  • Active Comparator: T1D group
    T1D group

Primary Outcome Measure

Apolipoprotein C turnover rate [ Time Frame: one time, at baseline (this is a cross-sectional, observational study, no intervention) ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of Missouri School of MedicineColumbiaMissouri65212
Bettina Mittendorfer, PhD
[email protected]

Find similar trials in Columbia, MO

By condition
Type 1 diabetes
By specialty
Endocrinology
By research site
University of Missouri School of Medicine· Columbia, MO

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