Supporting Treatment Access and Recovery in COD

Part of paid clinical trials in Holyoke, Massachusetts.

Sponsor
University of Massachusetts, Worcester
Study ID
NCT05138614
Status
Recruiting
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Conditions

  • Mental Health Disorder
  • Opioid Use Disorder

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Medication for Opioid Use Disorder — OTHER
    medication management
  • MISSION Critical Time Intervention — BEHAVIORAL
    offering intensive community-based services that decrease in intensity over time
  • MISSION Peer Support — BEHAVIORAL
    including 11 recovery-oriented sessions from someone with lived experience of co-occurring disorders
  • MISSION Dual Recovery Therapy — BEHAVIORAL
    comprised of 13 structured co-occurring disorders treatment sessions

Study Details

This 4-year study will randomize 1,000 people with co-occurring opioid use and mental health disorders (COD) at medication for opioid use disorder (MOUD) clinics to evaluate the effectiveness of MISSION, a multi-component team approach, or its components with MOUD versus MOUD alone, as well as the incremental benefits of MISSION or its components for improving outcomes. We expect that individuals receiving MISSION or its parts + MOUD will show greater improvement over MOUD alone on: engagement, substance use, and mental health.

Key Dates

Start date
Mar 11, 2022
Status verified
Jun 2026
Primary completion
Aug 31, 2026
Completion
Aug 31, 2026

Study Design

Enrollment
1,000 participants (estimated)
Allocation
RANDOMIZED
Intervention model
FACTORIAL
Primary purpose
TREATMENT

Arms

  • Experimental: Full MISSION
    CTI + DRT + PS + MOUD
  • Experimental: CTI & DRT
    CTI + DRT + MOUD
  • Experimental: CTI & PS
    CTI + PS + MOUD
  • Experimental: DRT & PS
    DRT + PS + MOUD
  • Other: MOUD only
    MOUD

Primary Outcome Measure

Engagement in treatment [ Time Frame: 6 months ]

Central Contacts

Locations (5)

FacilityCityStateZIPSite coordinators
Behavioral Health NetworkHolyokeMassachusetts01040
Herschelle Reaves
Behavioral Health NetworkOrangeMassachusetts01364
Calla Harrington
[email protected]
Behavioral Health NetworkSpringfieldMassachusetts01104
Herschelle Reaves
[email protected]
SaVida HealthWorcesterMassachusetts01605
Shelley Modzeleski
[email protected]
UMass Chan Road to Care ClinicWorcesterMassachusetts01601
Brittany Chapman
[email protected]

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