Post Mortem Tissue Donation of Pediatric Tumor Tissues and Cells

Part of paid clinical trials in Chicago, Illinois.

Sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Study ID
NCT05120518
Status
Recruiting
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Conditions

  • Pediatric Cancer

Eligibility Criteria

Sex
ALL
Age
N/A - N/A
Healthy Volunteers
Not accepted

Interventions

  • Collection of post mortem tissue donation — OTHER
    Collection of post mortem tissue from pediatric participants with cancer and non-cancer tumor types from whom post mortem tissue donation and autopsy consent is obtained.

Study Details

The objective of this study is to utilize all donated pediatric tumor tissues and cells obtained from autopsy to prospectively develop novel patient derived orthotopic xenograft (PDOX) mouse models as well as in vitro cell culture model systems for pediatric cancers, and also provide tissue samples to other researchers and organizations (eg, CBTN, DIPG Registry, COG).

Key Dates

Start date
Aug 14, 2019
Status verified
Jun 2026
Primary completion
Aug 14, 2029
Completion
Aug 14, 2029

Study Design

Enrollment
150 participants (estimated)

Arms

  • Arm: Pediatric patients with cancer and non-cancer tumor types
    Pediatric patients with cancer and non-cancer tumor types (solid, liquid, neuro-oncology and stem cell)

Primary Outcome Measure

Procurement of pediatric cancer and non-cancer tumor tissue during autopsy with signed consent [ Time Frame: Up to 5 years from procurement ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Ann & Robert H. Lurie Children's Hospital of ChicagoChicagoIllinois60611
Angela Waanders, MD
[email protected]
312-227-4090
Melissa Williams, BA
[email protected]
312-227-3893

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By research site
Ann & Robert H. Lurie Children's Hospital of Chicago· Chicago, IL

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