Latino Semaglutide Study

Part of paid clinical trials in Loma Linda, California.

Sponsor
Loma Linda University
Study ID
NCT05087342
Phase
PHASE3
Status
Completed

Conditions

  • Obesity
  • Obesity; Drug
  • Overweight or Obesity
  • Weight Loss
  • Weight Loss Trajectory
  • Weight, Body

Eligibility Criteria

Sex
ALL
Age
18 Years - 75 Years
Healthy Volunteers
Not accepted

Interventions

  • Semaglutide 2.4mg — DRUG
    The intervention drug, semaglutide 2.4mg will be given to the Intervention Group per the schedule outlined in the armed description.
  • Placebo — DRUG
    A placebo will be given to the control group per the schedule outlined in the armed description.

Study Details

The purpose of this study to understand better how this anti-obesity medication works to assist individuals to lose weight and maintain weight loss. This study may lead to the development of other related medications for assisting people with the disease of obesity.

Key Dates

Start date
Dec 13, 2022
Status verified
Oct 2024
Primary completion
May 29, 2024
Completion
May 29, 2024

Study Design

Enrollment
119 participants (actual)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Active Comparator: Intervention Group
    Will receive active medication semaglutide subcutaneously, once weekly, self-injection. Month 1 - 0.24 mg SC once weekly x 4 weeks.(IE-1) Month 2- 0.5 mg SC once weekly x 4 weeks.(IE-2) Month 3 -1 mg SC once weekly x 4 weeks.(IE-3) Month 4 - 1.7 mg SC once weekly x 4 weeks.(IE-4) Month 5 - 2.4 mg SC once weekly x 4 weeks. (IE-5) Month 6 - 2.4 mg SC continue once weekly x 8 weeks.(IE-6) Month 7 - completion visit (IE-7)
  • Placebo Comparator: Control Group
    Will receive placebo, subcutaneously, once weekly, self-injection throughout study duration.

Primary Outcome Measure

Assessment of weight loss. [ Time Frame: Change between baseline and final study visit, seven months post baseline. ]

Locations (1)

FacilityCityStateZIPSite coordinators
Loma Linda University HealthLoma LindaCalifornia92350-

Find similar trials in Loma Linda, CA

By condition
Obesity / overweight
By specialty
EndocrinologyMetabolic healthWeight loss
By research site
Loma Linda University Health· Loma Linda, CA

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