Vaccine Responses to SARS-CoV-2 and Other Emerging Infectious Diseases

Part of paid clinical trials in Bethesda, Maryland.

Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Study ID
NCT05078905
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Accepted

Study Details

Background: Vaccines against SARS-CoV-2, the virus that causes COVID-19, have been highly effective against preventing severe disease. But the protective effects of these vaccines appear to wane over time. Researchers want to learn why. Objective: To learn more about how the immune system responds to vaccines against infections like SARS-CoV-2. Eligibility: Healthy adults ages 18 or older who are scheduled to receive either a new vaccine or a booster shot against SARS-COV-2 or another emerging infection. Design: Participants will be screened with a medical history and blood and urine tests. Participants will have up to 8 study visits in 1 year. Each visit should last less than 2 hours. At each visit, participants will give blood samples. Some blood samples will be used for genetic testing. They will also give updates on their health. After the first study visit, participants will receive either a first vaccination or a booster shot. They must get the vaccine in their community or workplace. They will not get the vaccine at NIH. This study currently focuses on SARS-CoV-2, but it will expand to other infectious diseases as they emerge and become the target of new vaccines. ...

Key Dates

Start date
Oct 13, 2021
Status verified
May 2026
Primary completion
Jan 1, 2050
Completion
Jan 1, 2050

Study Design

Enrollment
1,200 participants (estimated)

Arms

  • Arm: Individuals Receiving Vaccine
    Individuals receiving a vaccination for an emerging infection, like SARS-CoV-2

Primary Outcome Measure

Characterize longitudinal serologic and cellular responses to vaccination to SARS-CoV-2 and other emerging infections. [ Time Frame: throughout ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
National Institutes of Health Clinical CenterBethesdaMaryland20892
For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)
[email protected]
800-411-1222

Find similar trials in Bethesda, MD

By condition
COVID-19 / long COVID
By specialty
Infectious disease
By research site
National Institutes of Health Clinical Center· Bethesda, MD

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