Safety, Pharmacokinetics, and Efficacy of AT 1501 in Patients Undergoing Kidney Transplant

Part of paid clinical trials in Cincinnati, Ohio.

Sponsor
Eledon Pharmaceuticals
Study ID
NCT05027906
Phase
PHASE1/PHASE2
Status
Recruiting

Conditions

  • Prevention of Rejection in Kidney Transplant

Eligibility Criteria

Sex
ALL
Age
18 Years - 100 Years
Healthy Volunteers
Not accepted

Interventions

  • AT-1501 — DRUG
    Investigative Arm

Study Details

This study will evaluate the safety, PK, and efficacy of AT 1501 in patients undergoing kidney transplantation.

Key Dates

Start date
Feb 18, 2022
Status verified
Jun 2025
Primary completion
Jan 31, 2027
Completion
Jan 31, 2027

Study Design

Enrollment
48 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: AT-1501 Single Arm
    AT-1501 monoclonal antibody targeting CD40L given as an IV infusion

Primary Outcome Measure

Safety Incidences [ Time Frame: Through study completion, an average up to 20 months ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of CincinnatiCincinnatiOhio45267
Research Staff

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