Fitness and Lung Function Among Survivors of Heart Transplant, Leukemia and Infant BPD Through Exercise

Part of paid clinical trials in Minneapolis, Minnesota.

Sponsor
Masonic Cancer Center, University of Minnesota
Study ID
NCT05025774
Status
Recruiting

Conditions

Eligibility Criteria

Sex
ALL
Age
8 Years - 25 Years
Healthy Volunteers
Not accepted

Interventions

  • Physical activity — OTHER
    Participant Reported Physical Activity and Outcomes (completed via REDCap or on paper)

Study Details

This study aims to more accurately assess cardiac function, ventilation and exercise capacity in a non-invasive fashion, and to better characterize exercise intolerance in the setting of three populations of individuals with chronic diseases of childhood (acute lymphoblastic leukemia (ALL), chronic lung disease (CLD) of prematurity, and post-heart transplant (HT))

Key Dates

Start date
Mar 14, 2025
Status verified
Nov 2025
Primary completion
Nov 1, 2026
Completion
Dec 1, 2026

Study Design

Enrollment
90 participants (estimated)

Arms

  • Arm: Case
    Adolescent or young adult acute lymphoblastic leukemia survivor, OR living with chronic lung disease of prematurity, OR living with heart transplant
  • Arm: Control
    14-25 years old healthy individuals who are ambulatory without assistance. We may enroll younger subjects but we wish to subjects to match our patient population

Primary Outcome Measure

Measure of Peak O2 intake during test exercise [ Time Frame: 3-4 hours during the onetime study visit day ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Masonic Cancer CenterMinneapolisMinnesota55455
Lucie Turcotte, MD, MPH, MS
612-624-1818

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