Extracellular RNA Biomarkers of Duchenne Muscular Dystrophy

Part of paid clinical trials in Boston, Massachusetts.

Sponsor
Massachusetts General Hospital
Study ID
NCT05016908
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
5 Years - N/A
Healthy Volunteers
Not accepted

Study Details

Current methods of measuring the response to new treatments for muscular dystrophies involve the examination of small pieces of muscle tissue called biopsies. The investigators are interested in finding less invasive methods that reduce the need for muscle biopsies. The purpose of this research is to learn about the possibility of detecting and measuring the activity and severity of muscular dystrophies by examining a urine sample and a blood sample.

Key Dates

Start date
Nov 30, 2019
Status verified
Oct 2025
Primary completion
Nov 30, 2026
Completion
Nov 30, 2027

Study Design

Enrollment
100 participants (estimated)

Arms

  • Arm: Biofluid collection
    Eligible volunteers will be asked to provide a single urine sample and undergo a single blood draw.

Primary Outcome Measure

Extracellular RNA in biofluids [ Time Frame: 4 years ]

Central Contacts

Locations (2)

FacilityCityStateZIPSite coordinators
Boston Children's HospitalBostonMassachusetts02115-
Massachusetts General HospitalBostonMassachusetts02129
Tamkin Shahraki, MD
[email protected]
617-726-7506
Thurman M. Wheeler, MD (PRINCIPAL_INVESTIGATOR)

Find similar trials in Boston, MA

By condition
Duchenne muscular dystrophy
By specialty
Pediatrics
By research site
Boston Children's Hospital· Boston, MAMassachusetts General Hospital· Boston, MA

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