Proprioceptive Sensorimotor Integration With Neural Interfaces for Hand Prostheses

Conditions

• Upper Limb Amputees

Eligibility Criteria

Sex

ALL

Age

18 Years - N/A

Healthy Volunteers

Not accepted

Interventions

• Chronically Implanted Neural and Muscular Interface — DEVICE
  Participants will be chronically implanted with neural and muscular interfaces to characterize proprioceptive sensations using Functional Electrical Stimulation (FES).

Study Details

The purpose of this study is to characterize proprioceptive sensations in the missing limb of upper limb amputees using nerve stimulation, and to develop advanced controllers for moving a prosthesis. Proprioceptive sensations are the sensations that tell individuals where their hand is in space, and if it is moving. The research team uses Functional Electrical Stimulation (FES), which involves applying small electric currents to the nerves. These signals are then transferred to the brain just like the information about the individual's intact hand used to be transferred to their brain. This study will test different placements for stimulation and determine which one(s) provide the individual with proprioceptive sensations. The investigators want to know what the participants feel and if the investigators can use proprioceptive sensation to give the participants information about limb movement and position.

Key Dates

Start date

Dec 1, 2021

Status verified

May 2026

Primary completion

May 31, 2030

Completion

May 31, 2030

Study Design

Enrollment

8 participants (estimated)

Allocation

NA

Intervention model

SINGLE_GROUP

Primary purpose

DEVICE_FEASIBILITY

Arms

• Experimental: Chronically Implanted Neural and Muscular Interface
  8 eligible participants will be chronically implanted with neural and muscular interfaces to characterize proprioceptive sensations using Functional Electrical Stimulation (FES).

Primary Outcome Measure

Magnitude of change in perceived joint position [ Time Frame: This metric will be measured approximately each month for two years. ]

Central Contacts

• Emily L Graczyk, PhD
  (216) 791-3800
  [email protected]
• Jessica R Jarvela, MS BS
  (216) 791-3800
  [email protected]

Locations (1)

Find similar trials in Cleveland, OH