Effect of Intermittent Hypoxia in Healthy Individuals

Part of paid clinical trials in Chicago, Illinois.

Sponsor
Shirley Ryan AbilityLab
Study ID
NCT04691518
Status
Enrolling By Invitation

Conditions

  • Healthy

Eligibility Criteria

Sex
ALL
Age
18 Years - 70 Years
Healthy Volunteers
Accepted

Interventions

  • Acute Intermittent Hypoxia — OTHER
    30 minute session of Acute Intermittent Hypoxia
  • Sham Acute Intermittent Hypoxia — OTHER
    30 minute session of Sham Acute Intermittent Hypoxia

Study Details

The use of acute intermittent hypoxia (AIH) has been examined in animal and human studies to gain an understanding of its effect on spinal excitability and synaptic strength. Subsequently, the investigators have learned that the use of AIH results in new protein formation and spinal plasticity. The use of acute intermittent hypoxia demonstrates a potential for therapeutic utilization in individuals with neurologic injuries. However, little is known about the effect of AIH in healthy individuals. This work is necessary to understand the mechanisms of AIH-induced plasticity. As such, this research study seeks to evaluate the impact of a single session AIH on upper extremity motor function in healthy individuals.

Key Dates

Start date
Nov 16, 2016
Status verified
Mar 2026
Primary completion
Mar 1, 2022
Completion
Jun 1, 2026

Study Design

Enrollment
32 participants (estimated)
Allocation
NON_RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE

Arms

  • Active Comparator: Acute Intermittent Hypoxia (AIH)
    Undergoing Acute Intermittent Hypoxia sessions
  • Placebo Comparator: Sham AIH
    Undergoing Sham AIH sessions

Primary Outcome Measure

Change in Grip Strength [ Time Frame: Immediately after acute intermittent hypoxia administration ]

Locations (1)

FacilityCityStateZIPSite coordinators
Shirley Ryan AbilityLabChicagoIllinois60611-

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Shirley Ryan AbilityLab· Chicago, IL

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