A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes Who Have Obesity or Are Overweight

Part of paid clinical trials in Birmingham, Alabama.

Sponsor
Eli Lilly and Company
Study ID
NCT04657003
Phase
PHASE3
Status
Completed

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Tirzepatide — DRUG
    Administered SC
  • Placebo — OTHER
    Administered SC

Study Details

This is a study of tirzepatide in participants with type 2 diabetes who have obesity or are overweight. The main purpose is to learn more about how tirzepatide affects body weight. The study will last 79 weeks (22 visits).

Key Dates

Start date
Mar 29, 2021
Status verified
Mar 2024
Primary completion
Mar 16, 2023
Completion
Apr 10, 2023

Study Design

Enrollment
938 participants (actual)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: 10 milligrams (mg) Tirzepatide
    10 mg Tirzepatide administered subcutaneously (SC) once weekly (QW)
  • Experimental: 15 mg Tirzepatide
    15 mg Tirzepatide administered SC QW
  • Placebo Comparator: Placebo
    Placebo administered SC QW

Primary Outcome Measure

Percent Change From Baseline in Body Weight [ Time Frame: Baseline, Week 72 ]

Locations (43)

FacilityCityStateZIPSite coordinators
University of Alabama - Department of Nutrition SciencesBirminghamAlabama35294-
KLR Business Group, Inc. dba Arkansas Clinical ResearchLittle RockArkansas72205-
Velocity Clinical Research, Huntington ParkHuntington ParkCalifornia90255-
Velocity Clinical Research, WestlakeLos AngelesCalifornia90057-
Catalina Research Institute, LLCMontclairCalifornia91763-
Encompass Clinical ResearchSpring ValleyCalifornia91978-
University Clinical Investigators, Inc.TustinCalifornia92780-
ALL Medical Research, LLCCooper CityFlorida33024-
Northeast Research Institute (NERI)Fleming IslandFlorida32003-
New Horizon Research CenterMiamiFlorida33165-
West Orange EndocrinologyOcoeeFlorida34761-
Metabolic Research Institute, Inc.West Palm BeachFlorida33401-
Emory University School of Medicine- Grady CampusAtlantaGeorgia30303-
East Coast Institute for Research, LLCMaconGeorgia31210-
Pacific Diabetes & Endocrine CenterHonoluluHawaii96813-
Elite Clinical TrialsBlackfootIdaho83221-
Rocky Mountain Clinical ResearchIdaho FallsIdaho83404-
American Health Network of Indiana, LLC - GreenfieldGreenfieldIndiana46140-
Iowa Diabetes and Endocrinology Research CenterWest Des MoinesIowa50265-
Cotton O'Neil Clinical Research CenterTopekaKansas66606-
Maryland Cardiovascular SpecialistsBaltimoreMaryland21229-
MD Medical ResearchOxon HillMaryland20745-
NECCR PrimaCare ResearchFall RiverMassachusetts02721-
Arcturus Healthcare , PLC, Troy Internal Medicine Research DivisionTroyMichigan48098-
Logan Health ResearchKalispellMontana59901-
Premier ResearchTrentonNew Jersey08611-
University of North Carolina Medical CenterChapel HillNorth Carolina27514-
PharmQuestGreensboroNorth Carolina27408-
Wake Forest University Baptist Medical Center (WFUBMC)Winston-SalemNorth Carolina27157-
Velocity Clinical Research, ClevelandClevelandOhio44122-
Aventiv ResearchDublinOhio43016-
The Corvallis Clinic, P.C.CorvallisOregon97330-
Preferred Primary Care PhysiciansUniontownPennsylvania15401-
Center for NeurosciencesWarwickRhode Island02886-
Tribe Clinical Research, LLCGreenvilleSouth Carolina29607-
Texas Diabetes & Endocrinology, P.A.AustinTexas78749-
Dallas Diabetes Research CenterDallasTexas75230-
Diabetes and Thyroid Center of Fort WorthFort WorthTexas76132-
Endocrine Ips, PllcHoustonTexas77079-
Juno ResearchHoustonTexas77040-
Health Research of Hampton Roads, Inc.Newport NewsVirginia23606-
Rainier Clinical Research CenterRentonWashington98057-
Clinical Investigation SpecialistsKenoshaWisconsin53144-

Find similar trials in Birmingham, AL

By condition
Obesity / overweightType 2 diabetes
By specialty
EndocrinologyMetabolic healthWeight loss
By research site
University of Alabama - Department of Nutrition Sciences· Birmingham, ALKLR Business Group, Inc. dba Arkansas Clinical Research· Little Rock, ARVelocity Clinical Research, Huntington Park· Huntington Park, CAVelocity Clinical Research, Westlake· Los Angeles, CACatalina Research Institute, LLC· Montclair, CAEncompass Clinical Research· Spring Valley, CA

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