Pubertal Blockade and Estradiol Effects on Cardiometabolic Health for Transitioning Youth

Part of paid clinical trials in Aurora, Colorado.

Sponsor
University of Colorado, Denver
Study ID
NCT04596592
Status
Recruiting
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Conditions

  • Gender Dysphoria
  • Insulin Sensitivity
  • Transgenderism

Eligibility Criteria

Sex
ALL
Age
13 Years - 16 Years
Healthy Volunteers
Not accepted

Study Details

To evaluate the effect of estradiol with or without a prior gonadotropin releasing hormone analogue on insulin sensitivity and vascular function in transgender females compared to cisgender controls.

Key Dates

Start date
Feb 15, 2021
Status verified
Jun 2025
Primary completion
Jul 31, 2026
Completion
Jul 31, 2026

Study Design

Enrollment
90 participants (estimated)

Arms

  • Arm: Transgender
  • Arm: Cisgender

Primary Outcome Measure

Insulin sensitivity [ Time Frame: Change from baseline to 12 months ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Children's Hospital ColoradoAuroraColorado80045
Natalie Nokoff, MD
[email protected]
720-777-3607

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By research site
Children's Hospital Colorado· Aurora, CO

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