Effects of Blocking Blue Light at Night Post CABG, AVR, MVR, CABG AVR, CABG MVR, or SAH

Part of paid clinical trials in Morgantown, West Virginia.

Sponsor
West Virginia University
Study ID
NCT04578249
Status
Recruiting
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Conditions

  • Circadian Rhythm Disorders

Eligibility Criteria

Sex
ALL
Age
45 Years - 75 Years
Healthy Volunteers
Not accepted

Interventions

  • Blue light-blocking goggles — OTHER
    Participants will be randomly assigned to one of the two intervention groups.
  • Clear goggles — OTHER
    Participants will be randomly assigned to one of the two intervention groups.

Study Details

Purpose The purpose of this study is to determine whether filtering out blue light at nighttime reduces post-surgical inflammation and/or moderates cognitive decline and mood and sleep alterations in patients undergoing elective CABG, AVR, MVR, CABG AVR, CABG MVR, or SAH surgery. If manipulating nighttime light in hospital rooms improves patient outcomes, then it would be a relatively easy and inexpensive innovation that could reduce post-surgical complications and save millions of dollars per year in health care costs by shortening the length of hospital stays and reducing morbidity. The investigators aim to determine the relationship between inflammation and cognitive dysfunction after cardiac surgery.

Key Dates

Start date
Sep 20, 2021
Status verified
Apr 2026
Primary completion
May 31, 2027
Completion
May 31, 2027

Study Design

Enrollment
80 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION

Arms

  • Placebo Comparator: Clear goggles
    Patients recovering from CABG, AVR, MVR, CABG AVR, CABG MVR, or SAH surgery will be given clear goggles to wear at nighttime.
  • Experimental: Blue-light blocking goggles
    Patients recovering from CABG, AVR, MVR, CABG AVR, CABG MVR, or SAH surgery will be given blue-light blocking goggles to wear at nighttime.

Primary Outcome Measure

Change in baseline serum cytokine profile [ Time Frame: 5 days post-surgery ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
West Virginia University Heart and Vascular InstituteMorgantownWest Virginia26506
James C. Walton, PhD
[email protected]
304.293.3490
Pallavi Sharma, PhD
[email protected]

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West Virginia University Heart and Vascular Institute· Morgantown, WV

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