Combination of Metronomic Capecitabine With Camrelizumab for Treatment of Refractory Solid Tumor Trial (Cohort 2)
- Sponsor
- Ruijin Hospital
- Study ID
- NCT04510818
- Phase
- PHASE1
- Status
- Unknown
Conditions
- Esophageal Squamous Cancer
- Head and Neck Cancer
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - N/A
- Healthy Volunteers
- Not accepted
Interventions
- Capecitabine, Camrelizumab — DRUGThis is a single-arm study with all patients receiving these two drugs.
Study Details
This is a single center phase 1 trail to observe safety and efficacy of metronomic Capecitabine plus Camrelizumab as second-line regimen to treat head and neck cancer or esophageal squamous cancer patients. This study is one of the cohorts of a multi-cohort trial called Combination of Metronomic Capecitabine with Camrelizumab for treatment of refractory solid tumor (McCrest) trial.
Key Dates
- Start date
- Aug 1, 2020
- Status verified
- Aug 2020
- Primary completion
- Aug 1, 2022
- Completion
- Aug 1, 2024
Study Design
- Enrollment
- 20 participants (estimated)
- Allocation
- NA
- Intervention model
- SINGLE_GROUP
- Primary purpose
- TREATMENT
Arms
- Experimental: ExperimentalCapecitabine 500mg bid. po. Camrelizumab 200mg ivgtt. d1 q2w
Primary Outcome Measure
Rate of adverse events as assessed by CTCAE v5.0 [ Time Frame: 48 months ]
Central Contacts
- Jing Liu+86-18001753364
- Chengfang Shangguan+86-13816860375
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